Sema4d GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Sema4d
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
MGI:109244

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0045499	chemorepellent activity	IBA	J:265628
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:22692
Molecular Function	GO:0030215	semaphorin receptor binding	IPI	J:178104
Molecular Function	GO:0030215	semaphorin receptor binding	ISO	J:164563
Molecular Function	GO:0030215	semaphorin receptor binding	IBA	J:265628
Molecular Function	GO:0038023	signaling receptor activity	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005102	signaling receptor binding	IPI	J:96745
Molecular Function	GO:0005102	signaling receptor binding	IPI	J:96745
Molecular Function	GO:0004888	transmembrane signaling receptor activity	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IDA	J:178104
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0016020	membrane	TAS	J:178104
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007409	axonogenesis	IGI	J:96745
Biological Process	GO:0007409	axonogenesis	IGI	J:96745
Biological Process	GO:0007409	axonogenesis	IGI	J:96745
Biological Process	GO:0007409	axonogenesis	IDA	J:96745
Biological Process	GO:0007409	axonogenesis	IGI	J:96745
Biological Process	GO:0007409	axonogenesis	IDA	J:96745
Biological Process	GO:0007409	axonogenesis	IGI	J:96745
Biological Process	GO:0007409	axonogenesis	IGI	J:96745
Biological Process	GO:0007409	axonogenesis	IGI	J:96745
Biological Process	GO:0007409	axonogenesis	IGI	J:96745
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0070486	leukocyte aggregation	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0050919	negative chemotaxis	IBA	J:265628
Biological Process	GO:0010693	negative regulation of alkaline phosphatase activity	IDA	J:178104
Biological Process	GO:0010693	negative regulation of alkaline phosphatase activity	ISO	J:164563
Biological Process	GO:0010693	negative regulation of alkaline phosphatase activity	IBA	J:265628
Biological Process	GO:0048843	negative regulation of axon extension involved in axon guidance	IBA	J:265628
Biological Process	GO:0007162	negative regulation of cell adhesion	ISO	J:164563
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	IMP	J:178104
Biological Process	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	IDA	J:178104
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:178104
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0001755	neural crest cell migration	IBA	J:265628
Biological Process	GO:0043931	ossification involved in bone maturation	IMP	J:178104
Biological Process	GO:0043931	ossification involved in bone maturation	ISO	J:164563
Biological Process	GO:0043931	ossification involved in bone maturation	IBA	J:265628
Biological Process	GO:0050772	positive regulation of axonogenesis	IDA	J:96745
Biological Process	GO:0050772	positive regulation of axonogenesis	IGI	J:96745
Biological Process	GO:0050772	positive regulation of axonogenesis	IGI	J:96745
Biological Process	GO:0050772	positive regulation of axonogenesis	IGI	J:96745
Biological Process	GO:0050772	positive regulation of axonogenesis	IGI	J:96745
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	IDA	J:178104
Biological Process	GO:0030335	positive regulation of cell migration	IBA	J:265628
Biological Process	GO:0048672	positive regulation of collateral sprouting	ISO	J:164563
Biological Process	GO:0043547	positive regulation of GTPase activity	IMP	J:178104
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0043547	positive regulation of GTPase activity	IBA	J:265628
Biological Process	GO:1905704	positive regulation of inhibitory synapse assembly	IDA	J:198674
Biological Process	GO:1905704	positive regulation of inhibitory synapse assembly	IMP	J:268255
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	IDA	J:178104
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0031344	regulation of cell projection organization	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	ISO	J:164563
Biological Process	GO:0048814	regulation of dendrite morphogenesis	ISO	J:164563
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	ISO	J:164563
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	IBA	J:265628
Biological Process	GO:1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis	IMP	J:178104

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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