GO Annotations Graph

• Symbol: Adamts1
• Name: ADAM metallopeptidase with thrombospondin type 1 motif 1
• ID: MGI:109249

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008201	heparin binding	IDA	J:37648
Molecular Function	GO:0008201	heparin binding	IDA	J:54300
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004222	metalloendopeptidase activity	IBA	J:265628
Molecular Function	GO:0004222	metalloendopeptidase activity	ISO	J:73065
Molecular Function	GO:0004222	metalloendopeptidase activity	IMP	J:102464
Molecular Function	GO:0004222	metalloendopeptidase activity	IDA	J:102464
Molecular Function	GO:0008237	metallopeptidase activity	IEA	J:72247
Molecular Function	GO:0008237	metallopeptidase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:102464
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005604	basement membrane	IDA	J:102464
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:155856
Cellular Component	GO:0031410	cytoplasmic vesicle	IDA	J:86134
Cellular Component	GO:0031012	extracellular matrix	IBA	J:265628
Cellular Component	GO:0031012	extracellular matrix	IDA	J:54300
Cellular Component	GO:0031012	extracellular matrix	IDA	J:86134
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Biological Process	GO:0030198	extracellular matrix organization	IBA	J:265628
Biological Process	GO:0060347	heart trabecula formation	IMP	J:132583
Biological Process	GO:0001822	kidney development	IMP	J:102464
Biological Process	GO:0001822	kidney development	IMP	J:96781
Biological Process	GO:0016525	negative regulation of angiogenesis	ISO	J:56900
Biological Process	GO:0001542	ovulation from ovarian follicle	IMP	J:96781
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	ISO	J:164563
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	ISO	J:164563
Biological Process	GO:0006508	proteolysis	IBA	J:265628