GO Annotations Graph

• Symbol: Smn1
• Name: survival motor neuron 1
• ID: MGI:109257

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0017134	fibroblast growth factor binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:199583
Molecular Function	GO:0005515	protein binding	IPI	J:184463
Molecular Function	GO:0005515	protein binding	IPI	J:75917
Molecular Function	GO:0005515	protein binding	IPI	J:199583
Molecular Function	GO:0005515	protein binding	IPI	J:170496
Molecular Function	GO:0003723	RNA binding	IEA	J:60000
Molecular Function	GO:0003723	RNA binding	IEA	J:72247
Cellular Component	GO:0015030	Cajal body	ISO	J:164563
Cellular Component	GO:0015030	Cajal body	IDA	J:206033
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0030137	COPI-coated vesicle	IDA	J:170496
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:170496
Cellular Component	GO:0005737	cytoplasm	IDA	J:67781
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0097504	Gemini of coiled bodies	ISO	J:155856
Cellular Component	GO:0097504	Gemini of coiled bodies	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:170496
Cellular Component	GO:0030426	growth cone	IDA	J:170496
Cellular Component	GO:0030426	growth cone	IDA	J:170496
Cellular Component	GO:0043005	neuron projection	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:67781
Cellular Component	GO:0043204	perikaryon	ISO	J:164563
Cellular Component	GO:0032797	SMN complex	ISO	J:164563
Cellular Component	GO:0032797	SMN complex	IBA	J:265628
Cellular Component	GO:0034719	SMN-Sm protein complex	ISO	J:164563
Biological Process	GO:0007409	axonogenesis	IMP	J:158711
Biological Process	GO:0007019	microtubule depolymerization	IMP	J:158711
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0006397	mRNA processing	IEA	J:72247
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0033120	positive regulation of RNA splicing	IMP	J:183557
Biological Process	GO:0010975	regulation of neuron projection development	IGI	J:206033
Biological Process	GO:0008380	RNA splicing	IEA	J:60000
Biological Process	GO:0000387	spliceosomal snRNP assembly	IBA	J:265628