GO Annotations Graph

• Symbol: Trim28
• Name: tripartite motif-containing 28
• ID: MGI:109274

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0070087	chromo shadow domain binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:183833
Molecular Function	GO:0003677	DNA binding	IDA	J:188793
Molecular Function	GO:0035851	Krueppel-associated box domain binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:1990841	promoter-specific chromatin binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:161286
Molecular Function	GO:0005515	protein binding	IPI	J:222251
Molecular Function	GO:0005515	protein binding	IPI	J:213416
Molecular Function	GO:0005515	protein binding	IPI	J:172192
Molecular Function	GO:0005515	protein binding	IPI	J:210023
Molecular Function	GO:0005515	protein binding	IPI	J:243455
Molecular Function	GO:0005515	protein binding	IPI	J:118046
Molecular Function	GO:0005515	protein binding	IPI	J:283196
Molecular Function	GO:0005515	protein binding	IPI	J:265834
Molecular Function	GO:0005515	protein binding	IPI	J:222151
Molecular Function	GO:0005515	protein binding	IPI	J:222151
Molecular Function	GO:0005515	protein binding	IPI	J:222151
Molecular Function	GO:0005515	protein binding	IPI	J:157813
Molecular Function	GO:0005515	protein binding	IPI	J:92455
Molecular Function	GO:0005515	protein binding	IPI	J:178936
Molecular Function	GO:0005515	protein binding	IPI	J:37212
Molecular Function	GO:0005515	protein binding	IPI	J:55434
Molecular Function	GO:0005515	protein binding	IPI	J:164418
Molecular Function	GO:0005515	protein binding	IPI	J:147874
Molecular Function	GO:0005515	protein binding	IPI	J:58506
Molecular Function	GO:0005515	protein binding	IPI	J:164348
Molecular Function	GO:0005515	protein binding	IPI	J:94471
Molecular Function	GO:0005515	protein binding	IPI	J:92455
Molecular Function	GO:0004672	protein kinase activity	IDA	J:58506
Molecular Function	GO:0019789	SUMO transferase activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:118046
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:222151
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:92455
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0061630	ubiquitin protein ligase activity	IBA	J:265628
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0000785	chromatin	IDA	J:69273
Cellular Component	GO:0000791	euchromatin	IDA	J:58506
Cellular Component	GO:0000792	heterochromatin	IDA	J:58506
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	IDA	J:58506
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:118046
Cellular Component	GO:0005634	nucleus	IDA	J:164348
Cellular Component	GO:0005634	nucleus	IDA	J:147874
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:118046
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IBA	J:265628
Biological Process	GO:0006325	chromatin organization	IBA	J:265628
Biological Process	GO:0060028	convergent extension involved in axis elongation	IMP	J:178936
Biological Process	GO:0043045	DNA methylation involved in embryo development	IMP	J:183833
Biological Process	GO:0006281	DNA repair	ISO	J:164563
Biological Process	GO:0007566	embryo implantation	IMP	J:183833
Biological Process	GO:0060669	embryonic placenta morphogenesis	IMP	J:178936
Biological Process	GO:0001837	epithelial to mesenchymal transition	IDA	J:118046
Biological Process	GO:0001701	in utero embryonic development	IMP	J:183833
Biological Process	GO:0045087	innate immune response	ISO	J:164563
Biological Process	GO:0045087	innate immune response	IBA	J:265628
Biological Process	GO:0045087	innate immune response	IDA	J:147874
Biological Process	GO:0045087	innate immune response	IGI	J:147874
Biological Process	GO:1901536	negative regulation of DNA demethylation	IMP	J:183833
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IMP	J:172192
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:58506
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	IMP	J:188475
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	IDA	J:147874
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	IGI	J:147874
Biological Process	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	IMP	J:147874
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IGI	J:178936
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:37437
Biological Process	GO:0043388	positive regulation of DNA binding	IMP	J:147874
Biological Process	GO:0043388	positive regulation of DNA binding	IDA	J:147874
Biological Process	GO:0090309	positive regulation of DNA methylation-dependent heterochromatin formation	ISO	J:164563
Biological Process	GO:0090309	positive regulation of DNA methylation-dependent heterochromatin formation	IMP	J:188475
Biological Process	GO:0045739	positive regulation of DNA repair	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:118046
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:92455
Biological Process	GO:0032092	positive regulation of protein binding	ISO	J:155856
Biological Process	GO:0042307	positive regulation of protein import into nucleus	ISO	J:164563
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:58506
Biological Process	GO:0006468	protein phosphorylation	IDA	J:58506
Biological Process	GO:0016925	protein sumoylation	ISO	J:164563
Biological Process	GO:0016925	protein sumoylation	IBA	J:265628
Biological Process	GO:2000653	regulation of genetic imprinting	IMP	J:183833
Biological Process	GO:0044790	suppression of viral release by host	ISO	J:164563