GO Annotations Graph

• Symbol: Slpi
• Name: secretory leukocyte peptidase inhibitor
• ID: MGI:109297

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	ISO	J:164563
Molecular Function	GO:0004866	endopeptidase inhibitor activity	IDA	J:269644
Molecular Function	GO:0004866	endopeptidase inhibitor activity	ISO	J:164563
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0003729	mRNA binding	ISO	J:164563
Molecular Function	GO:0030414	peptidase inhibitor activity	IEA	J:72247
Molecular Function	GO:0030414	peptidase inhibitor activity	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:269644
Molecular Function	GO:0004867	serine-type endopeptidase inhibitor activity	ISO	J:164563
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005615	extracellular space	IDA	J:132933
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005794	Golgi apparatus	ISO	J:164563
Biological Process	GO:0019731	antibacterial humoral response	ISO	J:164563
Biological Process	GO:0019731	antibacterial humoral response	IMP	J:132933
Biological Process	GO:0019731	antibacterial humoral response	IBA	J:265628
Biological Process	GO:0042742	defense response to bacterium	IEA	J:60000
Biological Process	GO:0006955	immune response	IMP	J:82214
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IMP	J:132933
Biological Process	GO:0045087	innate immune response	IBA	J:265628
Biological Process	GO:0035821	modulation of process of another organism	ISO	J:164563
Biological Process	GO:0010466	negative regulation of peptidase activity	IEA	J:60000
Biological Process	GO:0032091	negative regulation of protein binding	ISO	J:164563
Biological Process	GO:0045071	negative regulation of viral genome replication	ISO	J:164563
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:82214