GO Annotations Graph

• Symbol: F7
• Name: coagulation factor VII
• ID: MGI:109325

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0004175	endopeptidase activity	ISO	J:155856
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IEA	J:60000
Molecular Function	GO:0004252	serine-type endopeptidase activity	ISO	J:164563
Molecular Function	GO:0008236	serine-type peptidase activity	IEA	J:60000
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:155856
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-549502
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:1905370	serine-type endopeptidase complex	ISO	J:164563
Cellular Component	GO:1905286	serine-type peptidase complex	ISO	J:164563
Cellular Component	GO:0031982	vesicle	ISO	J:155856
Biological Process	GO:0002543	activation of blood coagulation via clotting cascade	NAS	J:320303
Biological Process	GO:0007596	blood coagulation	NAS	J:320303
Biological Process	GO:0007596	blood coagulation	ISO	J:164563
Biological Process	GO:0007596	blood coagulation	ISO	J:155856
Biological Process	GO:0007596	blood coagulation	IBA	J:265628
Biological Process	GO:0007596	blood coagulation	IMP	J:44294
Biological Process	GO:0007598	blood coagulation, extrinsic pathway	NAS	J:320303
Biological Process	GO:0072378	blood coagulation, fibrin clot formation	NAS	J:320303
Biological Process	GO:0007597	blood coagulation, intrinsic pathway	NAS	J:320303
Biological Process	GO:0007599	hemostasis	IEA	J:60000
Biological Process	GO:0030194	positive regulation of blood coagulation	ISO	J:155856
Biological Process	GO:0002690	positive regulation of leukocyte chemotaxis	ISO	J:164563
Biological Process	GO:0002690	positive regulation of leukocyte chemotaxis	IBA	J:265628
Biological Process	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	ISO	J:164563
Biological Process	GO:0050927	positive regulation of positive chemotaxis	ISO	J:164563
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ISO	J:164563
Biological Process	GO:0016485	protein processing	ISO	J:164563
Biological Process	GO:0006508	proteolysis	ISO	J:164563
Biological Process	GO:0061476	response to anticoagulant	ISO	J:155856
Biological Process	GO:1905217	response to astaxanthin	ISO	J:155856
Biological Process	GO:0070723	response to cholesterol	ISO	J:155856
Biological Process	GO:0031667	response to nutrient levels	ISO	J:155856
Biological Process	GO:0009611	response to wounding	NAS	J:320303