Bnip3 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Bnip3
BCL2/adenovirus E1B interacting protein 3
MGI:109326

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0051020	GTPase binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	IPI	J:183674
Molecular Function	GO:0005515	protein binding	IPI	J:136548
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0005740	mitochondrial envelope	IEA	J:72247
Cellular Component	GO:0031966	mitochondrial membrane	ISO	J:164563
Cellular Component	GO:0031966	mitochondrial membrane	IDA	J:113908
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005741	mitochondrial outer membrane	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	ISO	J:73065
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0014069	postsynaptic density	IDA	J:187362
Biological Process	GO:0006915	apoptotic process	ISO	J:37511
Biological Process	GO:0048102	autophagic cell death	ISO	J:155856
Biological Process	GO:0050873	brown fat cell differentiation	IDA	J:137608
Biological Process	GO:0010659	cardiac muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0008219	cell death	ISO	J:155856
Biological Process	GO:0071279	cellular response to cobalt ion	ISO	J:164563
Biological Process	GO:0070301	cellular response to hydrogen peroxide	ISO	J:155856
Biological Process	GO:0071456	cellular response to hypoxia	ISO	J:73065
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0140507	granzyme-mediated programmed cell death signaling pathway	ISO	J:164563
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	IMP	J:117391
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	IGI	J:117391
Biological Process	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia	ISO	J:164563
Biological Process	GO:0043653	mitochondrial fragmentation involved in apoptotic process	ISO	J:164563
Biological Process	GO:0097345	mitochondrial outer membrane permeabilization	ISO	J:164563
Biological Process	GO:0097345	mitochondrial outer membrane permeabilization	IBA	J:265628
Biological Process	GO:0035694	mitochondrial protein catabolic process	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	IGI	J:136548
Biological Process	GO:0045837	negative regulation of membrane potential	ISO	J:164563
Biological Process	GO:0010637	negative regulation of mitochondrial fusion	ISO	J:164563
Biological Process	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process	ISO	J:155856
Biological Process	GO:0010917	negative regulation of mitochondrial membrane potential	ISO	J:155856
Biological Process	GO:0043069	negative regulation of programmed cell death	ISO	J:73065
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	IGI	J:136548
Biological Process	GO:0051402	neuron apoptotic process	ISO	J:155856
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:155856
Biological Process	GO:1903599	positive regulation of autophagy of mitochondrion	ISO	J:155856
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	ISO	J:155856
Biological Process	GO:0016239	positive regulation of macroautophagy	ISO	J:73065
Biological Process	GO:0051561	positive regulation of mitochondrial calcium ion concentration	ISO	J:155856
Biological Process	GO:0090141	positive regulation of mitochondrial fission	ISO	J:164563
Biological Process	GO:0010940	positive regulation of necrotic cell death	ISO	J:155856
Biological Process	GO:0043068	positive regulation of programmed cell death	ISO	J:164563
Biological Process	GO:0043068	positive regulation of programmed cell death	IBA	J:265628
Biological Process	GO:0043243	positive regulation of protein-containing complex disassembly	ISO	J:164563
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0072593	reactive oxygen species metabolic process	ISO	J:164563
Biological Process	GO:1903715	regulation of aerobic respiration	IMP	J:136548
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	ISO	J:164563
Biological Process	GO:0010821	regulation of mitochondrion organization	IMP	J:136548
Biological Process	GO:0009617	response to bacterium	IEP	J:190322
Biological Process	GO:0001666	response to hypoxia	ISO	J:155856
Biological Process	GO:1901998	toxin transport	IMP	J:197389

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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