GO Annotations Graph

• Symbol: Prop1
• Name: paired like homeodomain factor 1
• ID: MGI:109330

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	IPI	J:114817
Molecular Function	GO:0003682	chromatin binding	IDA	J:114817
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	J:114817
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	J:265628
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	J:114817
Molecular Function	GO:0005515	protein binding	IPI	J:114817
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:114817
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	J:265628
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:114817
Biological Process	GO:0021984	adenohypophysis development	IMP	J:143548
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:94409
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:79850
Biological Process	GO:0006915	apoptotic process	IMP	J:108961
Biological Process	GO:0001568	blood vessel development	IMP	J:108961
Biological Process	GO:0016477	cell migration	IGI	J:143548
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:94409
Biological Process	GO:0009953	dorsal/ventral pattern formation	IMP	J:79850
Biological Process	GO:0048732	gland development	IMP	J:108961
Biological Process	GO:0048850	hypophysis morphogenesis	IMP	J:114817
Biological Process	GO:0021979	hypothalamus cell differentiation	IMP	J:38548
Biological Process	GO:0021979	hypothalamus cell differentiation	IMP	J:38548
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:108961
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:114817
Biological Process	GO:0021983	pituitary gland development	IMP	J:73085
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:114817
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:114817
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0060126	somatotropin secreting cell differentiation	IMP	J:7211