GO Annotations Graph

• Symbol: Rap1gap
• Name: Rap1 GTPase-activating protein
• ID: MGI:109338

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005096	GTPase activator activity	ISO	J:164563
Molecular Function	GO:0005096	GTPase activator activity	IBA	J:265628
Molecular Function	GO:0030695	GTPase regulator activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:213588
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0031267	small GTPase binding	ISO	J:164563
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0030425	dendrite	ISO	J:155856
Cellular Component	GO:0005769	early endosome	ISO	J:155856
Cellular Component	GO:0005794	Golgi apparatus	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Biological Process	GO:0090630	activation of GTPase activity	IBA	J:265628
Biological Process	GO:0098609	cell-cell adhesion	IMP	J:213588
Biological Process	GO:1990792	cellular response to glial cell derived neurotrophic factor	ISO	J:155856
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:213588
Biological Process	GO:1904425	negative regulation of GTP binding	ISO	J:155856
Biological Process	GO:1903697	negative regulation of microvillus assembly	ISO	J:164563
Biological Process	GO:0045665	negative regulation of neuron differentiation	ISO	J:155856
Biological Process	GO:1904442	negative regulation of thyroid gland epithelial cell proliferation	ISO	J:155856
Biological Process	GO:0006909	phagocytosis	IMP	J:213588
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	IMP	J:213588
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	IMP	J:213588
Biological Process	GO:0043547	positive regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0050766	positive regulation of phagocytosis	IMP	J:213588
Biological Process	GO:0050766	positive regulation of phagocytosis	IMP	J:213588
Biological Process	GO:0043087	regulation of GTPase activity	ISO	J:164563
Biological Process	GO:0051056	regulation of small GTPase mediated signal transduction	IEA	J:72247