GO Annotations Graph

• Symbol: Kcnk2
• Name: potassium channel, subfamily K, member 2
• ID: MGI:109366

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015271	outward rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0005267	potassium channel activity	IEA	J:72247
Molecular Function	GO:0005267	potassium channel activity	IEA	J:60000
Molecular Function	GO:0019870	potassium channel inhibitor activity	ISO	J:155856
Molecular Function	GO:0022841	potassium ion leak channel activity	ISO	J:155856
Molecular Function	GO:0022841	potassium ion leak channel activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:229320
Molecular Function	GO:0005515	protein binding	IPI	J:119946
Molecular Function	GO:0005515	protein binding	IPI	J:159842
Molecular Function	GO:0005515	protein binding	IPI	J:184566
Molecular Function	GO:0005249	voltage-gated potassium channel activity	IDA	J:72776
Cellular Component	GO:0016324	apical plasma membrane	ISO	J:155856
Cellular Component	GO:0097449	astrocyte projection	ISO	J:155856
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0044305	calyx of Held	ISO	J:155856
Cellular Component	GO:0009986	cell surface	ISO	J:155856
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:155856
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:184566
Cellular Component	GO:0008076	voltage-gated potassium channel complex	IDA	J:72776
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	IDA	J:72776
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0060044	negative regulation of cardiac muscle cell proliferation	ISO	J:155856
Biological Process	GO:2000279	negative regulation of DNA biosynthetic process	ISO	J:155856
Biological Process	GO:0010942	positive regulation of cell death	ISO	J:155856
Biological Process	GO:1900039	positive regulation of cellular response to hypoxia	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0071805	potassium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	IDA	J:72776
Biological Process	GO:0042391	regulation of membrane potential	IGI	J:184566
Biological Process	GO:0042391	regulation of membrane potential	IGI	J:184566
Biological Process	GO:0042391	regulation of membrane potential	IGI	J:184566
Biological Process	GO:0030322	stabilization of membrane potential	IBA	J:265628
Biological Process	GO:0030322	stabilization of membrane potential	TAS	J:72776