GO Annotations Graph

• Symbol: Cbx5
• Name: chromobox 5
• ID: MGI:109372

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	IBA	J:265628
Molecular Function	GO:0003682	chromatin binding	IDA	J:55698
Molecular Function	GO:0140297	DNA-binding transcription factor binding	IPI	J:152666
Molecular Function	GO:0042826	histone deacetylase binding	IPI	J:152666
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	IPI	J:37212
Molecular Function	GO:0035064	methylated histone binding	ISO	J:164563
Molecular Function	GO:0035064	methylated histone binding	IBA	J:265628
Molecular Function	GO:0035064	methylated histone binding	IPI	J:102885
Molecular Function	GO:0005515	protein binding	IPI	J:213416
Molecular Function	GO:0005515	protein binding	IPI	J:245338
Molecular Function	GO:0005515	protein binding	IPI	J:306882
Molecular Function	GO:0005515	protein binding	IPI	J:37212
Molecular Function	GO:0005515	protein binding	IPI	J:37212
Molecular Function	GO:0005515	protein binding	IPI	J:94471
Molecular Function	GO:0005515	protein binding	IPI	J:151987
Molecular Function	GO:0005515	protein binding	IPI	J:58506
Molecular Function	GO:0005515	protein binding	IPI	J:37212
Molecular Function	GO:0005515	protein binding	IPI	J:37212
Molecular Function	GO:0005515	protein binding	IPI	J:58506
Molecular Function	GO:0005515	protein binding	IPI	J:119141
Molecular Function	GO:0005515	protein binding	IPI	J:37212
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	IPI	J:152666
Molecular Function	GO:0043021	ribonucleoprotein complex binding	ISO	J:164563
Cellular Component	GO:0010369	chromocenter	IDA	J:180371
Cellular Component	GO:0010369	chromocenter	IDA	J:120756
Cellular Component	GO:0010369	chromocenter	IDA	J:158807
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000775	chromosome, centromeric region	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:160497
Cellular Component	GO:0000792	heterochromatin	IDA	J:55698
Cellular Component	GO:0000792	heterochromatin	IDA	J:87868
Cellular Component	GO:0000792	heterochromatin	IDA	J:90736
Cellular Component	GO:0000792	heterochromatin	IDA	J:99406
Cellular Component	GO:0000118	histone deacetylase complex	IDA	J:152666
Cellular Component	GO:0035097	histone methyltransferase complex	IDA	J:152666
Cellular Component	GO:0000776	kinetochore	IDA	J:86777
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	IDA	J:55698
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4616026
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:120756
Cellular Component	GO:0005634	nucleus	IDA	J:55698
Cellular Component	GO:0005721	pericentric heterochromatin	IDA	J:160497
Cellular Component	GO:0005721	pericentric heterochromatin	IBA	J:265628
Cellular Component	GO:0016605	PML body	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:1990904	ribonucleoprotein complex	ISO	J:164563
Cellular Component	GO:0090734	site of DNA damage	ISO	J:164563
Cellular Component	GO:0017053	transcription repressor complex	IDA	J:152666
Biological Process	GO:0006325	chromatin organization	IBA	J:265628
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	IDA	J:58506
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA	J:265628