GO Annotations Graph

• Symbol: Epha8
• Name: Eph receptor A8
• ID: MGI:109378

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005003	ephrin receptor activity	IEA	J:72247
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	IDA	J:177172
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	IDA	J:38350
Molecular Function	GO:0019838	growth factor binding	IPI	J:297316
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:177172
Molecular Function	GO:0005515	protein binding	IPI	J:177175
Molecular Function	GO:0005515	protein binding	IPI	J:129044
Molecular Function	GO:0005515	protein binding	IPI	J:38350
Molecular Function	GO:0005515	protein binding	IPI	J:161729
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:60000
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:72247
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEA	J:72245
Molecular Function	GO:0005005	transmembrane-ephrin receptor activity	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0030425	dendrite	IBA	J:265628
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IDA	J:129044
Cellular Component	GO:0005886	plasma membrane	IDA	J:38350
Biological Process	GO:0007411	axon guidance	IMP	J:41127
Biological Process	GO:0007411	axon guidance	IBA	J:265628
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	IDA	J:194293
Biological Process	GO:0048013	ephrin receptor signaling pathway	IDA	J:38350
Biological Process	GO:0048013	ephrin receptor signaling pathway	IDA	J:129044
Biological Process	GO:0048013	ephrin receptor signaling pathway	IDA	J:177172
Biological Process	GO:0048013	ephrin receptor signaling pathway	IBA	J:265628
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0031175	neuron projection development	IDA	J:177162
Biological Process	GO:0016322	neuron remodeling	IDA	J:129044
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0043410	positive regulation of MAPK cascade	IDA	J:177162
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	IDA	J:177172
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:177172
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:177175
Biological Process	GO:0006468	protein phosphorylation	IBA	J:265628
Biological Process	GO:0030155	regulation of cell adhesion	IDA	J:177175
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	IDA	J:177172
Biological Process	GO:0006929	substrate-dependent cell migration	IDA	J:129044
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	IEA	J:72247