GO Annotations Graph

• Symbol: Faf1
• Name: Fas-associated factor 1
• ID: MGI:109419

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:164563
Molecular Function	GO:0051059	NF-kappaB binding	ISO	J:164563
Molecular Function	GO:0051059	NF-kappaB binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:30163
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:30163
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0043130	ubiquitin binding	ISO	J:164563
Molecular Function	GO:0043130	ubiquitin binding	IBA	J:265628
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:73293
Cellular Component	GO:0005737	cytoplasm	IDA	J:73293
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005635	nuclear envelope	IDA	J:73293
Cellular Component	GO:0005635	nuclear envelope	IDA	J:73293
Cellular Component	GO:0005635	nuclear envelope	IDA	J:73293
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:1990917	ooplasm	IDA	J:73293
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:164563
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	ISO	J:164563
Biological Process	GO:0006915	apoptotic process	IEA	J:60000
Biological Process	GO:0008219	cell death	ISO	J:164563
Biological Process	GO:0007253	cytoplasmic sequestering of NF-kappaB	ISO	J:164563
Biological Process	GO:0010942	positive regulation of cell death	ISO	J:164563
Biological Process	GO:0010942	positive regulation of cell death	IBA	J:265628
Biological Process	GO:0045740	positive regulation of DNA replication	ISO	J:164563
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	IDA	J:30163
Biological Process	GO:0045732	positive regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	ISO	J:164563
Biological Process	GO:0030155	regulation of cell adhesion	IMP	J:73293
Biological Process	GO:0042176	regulation of protein catabolic process	ISO	J:164563
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	IBA	J:265628