GO Annotations Graph

• Symbol: Abca4
• Name: ATP-binding cassette, sub-family A member 4
• ID: MGI:109424

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005502	11-cis retinal binding	ISO	J:164563
Molecular Function	GO:0140359	ABC-type transporter activity	IEA	J:72247
Molecular Function	GO:0005503	all-trans retinal binding	ISO	J:164563
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0140326	ATPase-coupled intramembrane lipid transporter activity	IBA	J:265628
Molecular Function	GO:0140326	ATPase-coupled intramembrane lipid transporter activity	IMP	J:56317
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	TAS	J:48634
Molecular Function	GO:0140327	flippase activity	ISO	J:164563
Molecular Function	GO:0140347	N-retinylidene-phosphatidylethanolamine flippase activity	IMP	J:225104
Molecular Function	GO:0140347	N-retinylidene-phosphatidylethanolamine flippase activity	IMP	J:62911
Molecular Function	GO:0140347	N-retinylidene-phosphatidylethanolamine flippase activity	IMP	J:56317
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0090555	phosphatidylethanolamine flippase activity	ISO	J:164563
Molecular Function	GO:0005548	phospholipid transporter activity	IBA	J:265628
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IBA	J:265628
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0001750	photoreceptor outer segment	IDA	J:48634
Cellular Component	GO:0001750	photoreceptor outer segment	IDA	J:203124
Cellular Component	GO:0005886	plasma membrane	TAS	J:48634
Biological Process	GO:0034204	lipid translocation	IMP	J:56317
Biological Process	GO:0006869	lipid transport	IBA	J:265628
Biological Process	GO:0006649	phospholipid transfer to membrane	IMP	J:56317
Biological Process	GO:0045332	phospholipid translocation	ISO	J:164563
Biological Process	GO:0045494	photoreceptor cell maintenance	IMP	J:70248
Biological Process	GO:0050896	response to stimulus	IEA	J:60000
Biological Process	GO:0042574	retinal metabolic process	ISO	J:164563
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0007601	visual perception	IMP	J:56317