Cacna1a GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Cacna1a
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
MGI:109482

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005262	calcium channel activity	IEA	J:60000
Molecular Function	GO:0005516	calmodulin binding	ISO	J:155856
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	ISO	J:155856
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IBA	J:265628
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:82722
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:107960
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:63634
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:112100
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:82722
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:96814
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:72853
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:76879
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IGI	J:75166
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:76459
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:82722
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:109231
Molecular Function	GO:0008331	high voltage-gated calcium channel activity	IMP	J:109231
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0005216	monoatomic ion channel activity	IEA	J:72247
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0005515	protein binding	IPI	J:28892
Molecular Function	GO:0005515	protein binding	IPI	J:57712
Molecular Function	GO:0019905	syntaxin binding	ISO	J:164563
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:164563
Molecular Function	GO:0005245	voltage-gated calcium channel activity	ISO	J:155856
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:51647
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:106959
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:59076
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:51647
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IDA	J:31925
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:47984
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:89452
Molecular Function	GO:0005245	voltage-gated calcium channel activity	IMP	J:59076
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IDA	J:242456
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IDA	J:242456
Molecular Function	GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	IMP	J:242456
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Cellular Component	GO:0042995	cell projection	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0030425	dendrite	IDA	J:92975
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:242456
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:242456
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:242456
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0043025	neuronal cell body	ISO	J:155856
Cellular Component	GO:0043025	neuronal cell body	IBA	J:265628
Cellular Component	GO:0043025	neuronal cell body	IDA	J:92975
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0043204	perikaryon	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0005891	voltage-gated calcium channel complex	ISO	J:155856
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IBA	J:265628
Cellular Component	GO:0005891	voltage-gated calcium channel complex	IDA	J:57712
Biological Process	GO:0007628	adult walking behavior	IMP	J:36184
Biological Process	GO:0007628	adult walking behavior	IMP	J:5240
Biological Process	GO:0007628	adult walking behavior	IGI	J:36184
Biological Process	GO:0007628	adult walking behavior	IMP	J:5240
Biological Process	GO:0007628	adult walking behavior	IMP	MGI:MGI:63040
Biological Process	GO:0007628	adult walking behavior	IMP	J:107960
Biological Process	GO:0007628	adult walking behavior	IMP	J:262
Biological Process	GO:0007628	adult walking behavior	IMP	J:59076
Biological Process	GO:0007628	adult walking behavior	IMP	J:71860
Biological Process	GO:0007628	adult walking behavior	IMP	J:12735
Biological Process	GO:0007628	adult walking behavior	IGI	J:52508
Biological Process	GO:0007628	adult walking behavior	IMP	J:113141
Biological Process	GO:0007628	adult walking behavior	IMP	J:76459
Biological Process	GO:0048266	behavioral response to pain	IMP	J:113141
Biological Process	GO:0070509	calcium ion import	ISO	J:155856
Biological Process	GO:0098703	calcium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0070588	calcium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0006816	calcium ion transport	ISO	J:155856
Biological Process	GO:0006816	calcium ion transport	IMP	J:51647
Biological Process	GO:0006816	calcium ion transport	IMP	J:51647
Biological Process	GO:0006816	calcium ion transport	IMP	J:89452
Biological Process	GO:0006816	calcium ion transport	IMP	J:47984
Biological Process	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	IMP	J:60492
Biological Process	GO:0017156	calcium-ion regulated exocytosis	IMP	J:76879
Biological Process	GO:0008219	cell death	ISO	J:164563
Biological Process	GO:1904646	cellular response to amyloid-beta	ISO	J:164563
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:6615
Biological Process	GO:0021953	central nervous system neuron differentiation	IMP	J:6615
Biological Process	GO:0021679	cerebellar molecular layer development	IMP	J:22482
Biological Process	GO:0021679	cerebellar molecular layer development	IMP	J:22482
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IMP	J:14500
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IMP	J:58539
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IMP	J:14500
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	IMP	J:20921
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	IMP	J:14500
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	IMP	J:14500
Biological Process	GO:0021590	cerebellum maturation	IMP	J:76459
Biological Process	GO:0007268	chemical synaptic transmission	ISO	J:155856
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:109231
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:59076
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:96814
Biological Process	GO:0007268	chemical synaptic transmission	IMP	J:109231
Biological Process	GO:0048813	dendrite morphogenesis	IMP	J:71860
Biological Process	GO:0048813	dendrite morphogenesis	IMP	J:55268
Biological Process	GO:0048813	dendrite morphogenesis	IMP	J:90116
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:60492
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:51647
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:76879
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:51647
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:47984
Biological Process	GO:0014051	gamma-aminobutyric acid secretion	IMP	J:60492
Biological Process	GO:0007214	gamma-aminobutyric acid signaling pathway	IMP	J:32181
Biological Process	GO:0042593	glucose homeostasis	IMP	J:40690
Biological Process	GO:0042446	hormone biosynthetic process	IMP	J:110939
Biological Process	GO:0030644	intracellular chloride ion homeostasis	IMP	J:32181
Biological Process	GO:0030644	intracellular chloride ion homeostasis	IMP	J:103988
Biological Process	GO:0051899	membrane depolarization	IMP	J:18102
Biological Process	GO:0051899	membrane depolarization	IMP	J:63634
Biological Process	GO:0051899	membrane depolarization	IMP	J:72853
Biological Process	GO:0050804	modulation of chemical synaptic transmission	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:72247
Biological Process	GO:0050883	musculoskeletal movement, spinal reflex action	IMP	J:72853
Biological Process	GO:0032353	negative regulation of hormone biosynthetic process	IMP	J:110939
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:36596
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:36596
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:5240
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:5240
Biological Process	GO:0050877	nervous system process	IMP	J:3611
Biological Process	GO:0050877	nervous system process	IMP	J:7519
Biological Process	GO:0050905	neuromuscular process	IMP	J:76459
Biological Process	GO:0050905	neuromuscular process	IGI	J:58539
Biological Process	GO:0050885	neuromuscular process controlling balance	IMP	J:12735
Biological Process	GO:0007274	neuromuscular synaptic transmission	IMP	J:102080
Biological Process	GO:0007274	neuromuscular synaptic transmission	IMP	J:102080
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:36596
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:5240
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:5240
Biological Process	GO:0051402	neuron apoptotic process	IMP	J:36596
Biological Process	GO:0070050	neuron cellular homeostasis	IMP	J:103988
Biological Process	GO:0007270	neuron-neuron synaptic transmission	IMP	J:106709
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ISO	J:164563
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	IDA	J:31925
Biological Process	GO:0043113	receptor clustering	IMP	J:82722
Biological Process	GO:0014056	regulation of acetylcholine secretion, neurotransmission	IMP	J:102080
Biological Process	GO:0014056	regulation of acetylcholine secretion, neurotransmission	IMP	J:82722
Biological Process	GO:0050770	regulation of axonogenesis	IMP	J:6154
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	IDA	J:31925
Biological Process	GO:0010817	regulation of hormone levels	IMP	MGI:MGI:85368
Biological Process	GO:0010817	regulation of hormone levels	IMP	J:40690
Biological Process	GO:0010817	regulation of hormone levels	IMP	J:15508
Biological Process	GO:0010817	regulation of hormone levels	IMP	J:40690
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:47984
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:1180
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:51647
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:106959
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:51647
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:107960
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:3627
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:60492
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IEA	J:60000
Biological Process	GO:0001505	regulation of neurotransmitter levels	IMP	J:633
Biological Process	GO:0001505	regulation of neurotransmitter levels	IMP	J:633
Biological Process	GO:0001505	regulation of neurotransmitter levels	IMP	J:14712
Biological Process	GO:0001505	regulation of neurotransmitter levels	IMP	J:14712
Biological Process	GO:0001505	regulation of neurotransmitter levels	IMP	J:633
Biological Process	GO:0001505	regulation of neurotransmitter levels	IMP	J:6553
Biological Process	GO:0001505	regulation of neurotransmitter levels	IMP	J:633
Biological Process	GO:0031335	regulation of sulfur amino acid metabolic process	IMP	J:12200
Biological Process	GO:0031335	regulation of sulfur amino acid metabolic process	IMP	J:12200
Biological Process	GO:0031335	regulation of sulfur amino acid metabolic process	IMP	J:12200
Biological Process	GO:0031335	regulation of sulfur amino acid metabolic process	IMP	J:12200
Biological Process	GO:1901385	regulation of voltage-gated calcium channel activity	ISO	J:155856
Biological Process	GO:1904645	response to amyloid-beta	ISO	J:164563
Biological Process	GO:0048265	response to pain	IMP	J:72853
Biological Process	GO:0060024	rhythmic synaptic transmission	IMP	J:107094
Biological Process	GO:0019233	sensory perception of pain	ISO	J:155856
Biological Process	GO:0021522	spinal cord motor neuron differentiation	IMP	J:135940
Biological Process	GO:0021522	spinal cord motor neuron differentiation	IMP	J:135940
Biological Process	GO:0007416	synapse assembly	IMP	J:90116
Biological Process	GO:0007416	synapse assembly	IMP	J:55268
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IMP	J:56225
Biological Process	GO:0035249	synaptic transmission, glutamatergic	IMP	J:90116
Biological Process	GO:0055085	transmembrane transport	IEA	J:72247
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:3190
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:1180
Biological Process	GO:0019226	transmission of nerve impulse	IMP	J:3627
Biological Process	GO:0021750	vestibular nucleus development	IMP	J:30260

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