GO Annotations Graph

• Symbol: Ywhaz
• Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
• ID: MGI:109484

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0050815	phosphoserine residue binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:243395
Molecular Function	GO:0005515	protein binding	IPI	J:233569
Molecular Function	GO:0005515	protein binding	IPI	J:273540
Molecular Function	GO:0005515	protein binding	IPI	J:277876
Molecular Function	GO:0005515	protein binding	IPI	J:79740
Molecular Function	GO:0005515	protein binding	IPI	J:117469
Molecular Function	GO:0005515	protein binding	IPI	J:202594
Molecular Function	GO:0005515	protein binding	IPI	J:196255
Molecular Function	GO:0005515	protein binding	IPI	J:273513
Molecular Function	GO:0005515	protein binding	IPI	J:151342
Molecular Function	GO:0005515	protein binding	IPI	J:143074
Molecular Function	GO:0005515	protein binding	IPI	J:137945
Molecular Function	GO:0019904	protein domain specific binding	IDA	J:79740
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0140311	protein sequestering activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Cellular Component	GO:0031252	cell leading edge	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-1445145
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-1454713
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-9604388
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:164563
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:217297
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:217297
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IDA	J:217297
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	IMP	J:217297
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005634	nucleus	IDA	J:94966
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Cellular Component	GO:0099572	postsynaptic specialization	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Biological Process	GO:0001525	angiogenesis	IGI	J:254918
Biological Process	GO:0001525	angiogenesis	IMP	J:254918
Biological Process	GO:0070371	ERK1 and ERK2 cascade	IMP	J:254918
Biological Process	GO:0051683	establishment of Golgi localization	ISO	J:164563
Biological Process	GO:0090168	Golgi reassembly	ISO	J:164563
Biological Process	GO:0002553	histamine secretion by mast cell	ISO	J:155856
Biological Process	GO:0030324	lung development	IMP	J:254918
Biological Process	GO:0045824	negative regulation of innate immune response	ISO	J:164563
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IDA	J:243395
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006605	protein targeting	IDA	J:80612
Biological Process	GO:0006626	protein targeting to mitochondrion	ISO	J:155856
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0043067	regulation of programmed cell death	IGI	J:151342
Biological Process	GO:0090128	regulation of synapse maturation	ISO	J:164563
Biological Process	GO:0003016	respiratory system process	IMP	J:254918
Biological Process	GO:0009410	response to xenobiotic stimulus	ISO	J:155856
Biological Process	GO:0007165	signal transduction	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IBA	J:265628
Biological Process	GO:0008039	synaptic target recognition	IMP	J:217297
Biological Process	GO:0008039	synaptic target recognition	IDA	J:217297
Biological Process	GO:0008039	synaptic target recognition	IDA	J:217297
Biological Process	GO:0008039	synaptic target recognition	IDA	J:217297
Biological Process	GO:0035148	tube formation	IGI	J:254918
Biological Process	GO:0035148	tube formation	IMP	J:254918