GO Annotations Graph

• Symbol: Cdc37
• Name: cell division cycle 37
• ID: MGI:109531

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:164563
Molecular Function	GO:0031072	heat shock protein binding	IBA	J:265628
Molecular Function	GO:0051879	Hsp90 protein binding	IDA	J:117265
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0019900	kinase binding	IPI	J:215871
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:203314
Molecular Function	GO:0043422	protein kinase B binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:155856
Molecular Function	GO:0019887	protein kinase regulator activity	IDA	J:215871
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:155856
Molecular Function	GO:0051087	protein-folding chaperone binding	IBA	J:265628
Molecular Function	GO:0097110	scaffold protein binding	ISO	J:164563
Molecular Function	GO:0001222	transcription corepressor binding	ISO	J:155856
Molecular Function	GO:0051082	unfolded protein binding	IBA	J:265628
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:117265
Cellular Component	GO:1990565	HSP90-CDC37 chaperone complex	IDA	J:215871
Cellular Component	GO:1990565	HSP90-CDC37 chaperone complex	ISO	J:164563
Cellular Component	GO:0101031	protein folding chaperone complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032587	ruffle membrane	ISO	J:155856
Biological Process	GO:0098779	positive regulation of mitophagy in response to mitochondrial depolarization	IDA	J:215871
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	IDA	J:215871
Biological Process	GO:0006457	protein folding	IBA	J:265628
Biological Process	GO:0050821	protein stabilization	IBA	J:265628
Biological Process	GO:0045859	regulation of protein kinase activity	IDA	J:215871
Biological Process	GO:0060338	regulation of type I interferon-mediated signaling pathway	ISO	J:107465
Biological Process	GO:0060334	regulation of type II interferon-mediated signaling pathway	ISO	J:107465