GO Annotations Graph

• Symbol: Sf1
• Name: splicing factor 1
• ID: MGI:1095403

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0003729	mRNA binding	IBA	J:265628
Molecular Function	GO:0003676	nucleic acid binding	IEA	J:72247
Molecular Function	GO:0045131	pre-mRNA branch point binding	IEA	J:72247
Molecular Function	GO:0003723	RNA binding	IPI	J:230219
Molecular Function	GO:0008270	zinc ion binding	IEA	J:72247
Cellular Component	GO:0005737	cytoplasm	ISS	J:137212
Cellular Component	GO:0016604	nuclear body	IDA	J:230219
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	NAS	J:319982
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	ISS	J:137212
Cellular Component	GO:0005681	spliceosomal complex	ISO	J:164563
Cellular Component	GO:0089701	U2AF complex	ISO	J:164563
Biological Process	GO:0033327	Leydig cell differentiation	IGI	J:129625
Biological Process	GO:0033327	Leydig cell differentiation	IGI	J:129625
Biological Process	GO:0030238	male sex determination	IGI	J:129625
Biological Process	GO:0006397	mRNA processing	IEA	J:60000
Biological Process	GO:0000398	mRNA splicing, via spliceosome	NAS	J:319982
Biological Process	GO:0048662	negative regulation of smooth muscle cell proliferation	ISO	J:155856
Biological Process	GO:0030575	nuclear body organization	IMP	J:230219
Biological Process	GO:0048024	regulation of mRNA splicing, via spliceosome	IBA	J:265628
Biological Process	GO:0050810	regulation of steroid biosynthetic process	IGI	J:129625
Biological Process	GO:0008380	RNA splicing	IEA	J:60000