GO Annotations Graph

• Symbol: Unc5c
• Name: unc-5 netrin receptor C
• ID: MGI:1095412

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005042	netrin receptor activity	IDA	J:64213
Molecular Function	GO:0005043	netrin receptor activity involved in chemorepulsion	IDA	J:269564
Molecular Function	GO:0005043	netrin receptor activity involved in chemorepulsion	IDA	J:242688
Molecular Function	GO:0005515	protein binding	IPI	J:269564
Molecular Function	GO:0005515	protein binding	IPI	J:242688
Molecular Function	GO:0005515	protein binding	IPI	J:64213
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0015631	tubulin binding	ISO	J:164563
Molecular Function	GO:0015631	tubulin binding	IPI	J:242688
Cellular Component	GO:0030424	axon	IDA	J:269564
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0030425	dendrite	IDA	J:269564
Cellular Component	GO:0030175	filopodium	IDA	J:242688
Cellular Component	GO:0030426	growth cone	IDA	J:269564
Cellular Component	GO:0030426	growth cone	IDA	J:242688
Cellular Component	GO:0030027	lamellipodium	IDA	J:242688
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043005	neuron projection	IEA	J:60000
Cellular Component	GO:0043025	neuronal cell body	IDA	J:269564
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-418862
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-418870
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-421687
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-NUL-421695
Cellular Component	GO:0005886	plasma membrane	IDA	J:64213
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0033564	anterior/posterior axon guidance	IMP	J:139365
Biological Process	GO:0033564	anterior/posterior axon guidance	IMP	J:139365
Biological Process	GO:0006915	apoptotic process	IMP	J:132146
Biological Process	GO:0007411	axon guidance	IGI	J:269564
Biological Process	GO:0007411	axon guidance	IDA	J:269564
Biological Process	GO:0007411	axon guidance	IGI	J:192361
Biological Process	GO:0007420	brain development	IMP	J:1827
Biological Process	GO:0007420	brain development	IMP	J:40243
Biological Process	GO:0007420	brain development	IMP	J:62291
Biological Process	GO:0007420	brain development	IMP	J:40243
Biological Process	GO:0007420	brain development	IMP	J:46670
Biological Process	GO:0061643	chemorepulsion of axon	IMP	J:242688
Biological Process	GO:1990791	dorsal root ganglion development	ISO	J:164563
Biological Process	GO:0035234	ectopic germ cell programmed cell death	IMP	J:132146
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0038007	netrin-activated signaling pathway	IGI	J:269564
Biological Process	GO:0043065	positive regulation of apoptotic process	IMP	J:132146
Biological Process	GO:0051094	positive regulation of developmental process	IMP	J:132146
Biological Process	GO:2000243	positive regulation of reproductive process	IMP	J:132146
Biological Process	GO:0030334	regulation of cell migration	IMP	J:62291
Biological Process	GO:2001222	regulation of neuron migration	IMP	J:45577
Biological Process	GO:0007165	signal transduction	IEA	J:72247