GO Annotations Graph

• Symbol: Kmt2b
• Name: lysine (K)-specific methyltransferase 2B
• ID: MGI:109565

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003677	DNA binding	IEA	J:72247
Molecular Function	GO:0003677	DNA binding	IEA	J:60000
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	ISO	J:164563
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IBA	J:265628
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IDA	J:307409
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	ISO	J:123598
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	IMP	J:166778
Molecular Function	GO:0140945	histone H3K4 monomethyltransferase activity	IEA	J:72245
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008168	methyltransferase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0045322	unmethylated CpG binding	ISO	J:164563
Molecular Function	GO:0008270	zinc ion binding	ISO	J:164563
Cellular Component	GO:0035097	histone methyltransferase complex	IBA	J:265628
Cellular Component	GO:0035097	histone methyltransferase complex	ISO	J:123598
Cellular Component	GO:0044665	MLL1/2 complex	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:123598
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006346	DNA methylation-dependent heterochromatin formation	IMP	J:166778
Biological Process	GO:0051568	histone H3-K4 methylation	IBA	J:265628
Biological Process	GO:0160021	maternal-to-zygotic transition of gene expression	IMP	J:166778
Biological Process	GO:0160021	maternal-to-zygotic transition of gene expression	IMP	J:166778
Biological Process	GO:0032259	methylation	IEA	J:60000
Biological Process	GO:0048599	oocyte development	IMP	J:166778
Biological Process	GO:0001541	ovarian follicle development	IMP	J:166778
Biological Process	GO:0001541	ovarian follicle development	IMP	J:166778
Biological Process	GO:0030728	ovulation	IMP	J:166778
Biological Process	GO:0030728	ovulation	IMP	J:166778
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:0006355	regulation of DNA-templated transcription	IEA	J:72247