GO Annotations Graph

• Symbol: Atp6ap1
• Name: ATPase, H+ transporting, lysosomal accessory protein 1
• ID: MGI:109629

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001671	ATPase activator activity	IMP	J:220934
Molecular Function	GO:0031267	small GTPase binding	IPI	J:211452
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	IEA	J:60000
Cellular Component	GO:0010008	endosome membrane	IMP	J:220934
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0033176	proton-transporting V-type ATPase complex	IBA	J:265628
Cellular Component	GO:0045202	synapse	IEA	J:60000
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Biological Process	GO:0008219	cell death	ISO	J:155856
Biological Process	GO:0036295	cellular response to increased oxygen levels	ISO	J:164563
Biological Process	GO:0099638	endosome to plasma membrane protein transport	IMP	J:211452
Biological Process	GO:0006879	intracellular iron ion homeostasis	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:0036035	osteoclast development	IMP	J:211452
Biological Process	GO:0030641	regulation of cellular pH	IBA	J:265628
Biological Process	GO:0097401	synaptic vesicle lumen acidification	EXP	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IMP	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IDA	J:326652
Biological Process	GO:0097401	synaptic vesicle lumen acidification	IDA	J:326652