GO Annotations Graph

• Symbol: Bad
• Name: BCL2-associated agonist of cell death
• ID: MGI:1096330

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	ISO	J:155856
Molecular Function	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	ISO	J:164563
Molecular Function	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	IDA	J:160042
Molecular Function	GO:0008289	lipid binding	ISO	J:164563
Molecular Function	GO:0005543	phospholipid binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:235310
Molecular Function	GO:0005515	protein binding	IPI	J:203396
Molecular Function	GO:0005515	protein binding	IPI	J:116441
Molecular Function	GO:0005515	protein binding	IPI	J:173139
Molecular Function	GO:0005515	protein binding	IPI	J:133563
Molecular Function	GO:0005515	protein binding	IPI	J:128448
Molecular Function	GO:0005515	protein binding	IPI	J:160042
Molecular Function	GO:0005515	protein binding	IPI	J:193499
Molecular Function	GO:0005515	protein binding	IPI	J:114705
Molecular Function	GO:0005515	protein binding	IPI	J:133563
Molecular Function	GO:0005515	protein binding	IPI	J:182384
Molecular Function	GO:0005515	protein binding	IPI	J:200331
Molecular Function	GO:0005515	protein binding	IPI	J:200329
Molecular Function	GO:0005515	protein binding	IPI	J:42326
Molecular Function	GO:0005515	protein binding	IPI	J:85463
Molecular Function	GO:0005515	protein binding	IPI	J:78230
Molecular Function	GO:0005515	protein binding	IPI	J:78230
Molecular Function	GO:0005515	protein binding	IPI	J:85083
Molecular Function	GO:0005515	protein binding	IPI	J:101937
Molecular Function	GO:0005515	protein binding	IPI	J:101937
Molecular Function	GO:0005515	protein binding	IPI	J:85083
Molecular Function	GO:0005515	protein binding	IPI	J:101937
Molecular Function	GO:0005515	protein binding	IPI	J:42326
Molecular Function	GO:0043422	protein kinase B binding	ISO	J:155856
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0030346	protein phosphatase 2B binding	ISO	J:155856
Molecular Function	GO:0019903	protein phosphatase binding	IPI	J:85463
Cellular Component	GO:0097138	BAD-BCL-2 complex	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:203396
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IDA	J:194718
Cellular Component	GO:0005737	cytoplasm	IDA	J:66494
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-3139045
Cellular Component	GO:0005829	cytosol	IDA	J:76215
Cellular Component	GO:0005829	cytosol	ISO	J:83681
Cellular Component	GO:0005829	cytosol	IDA	J:167678
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005741	mitochondrial outer membrane	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	IDA	J:85083
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	ISO	J:164563
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	IBA	J:265628
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	IDA	J:160042
Biological Process	GO:0046031	ADP metabolic process	IMP	J:133563
Biological Process	GO:0006915	apoptotic process	ISO	J:164563
Biological Process	GO:0097190	apoptotic signaling pathway	IMP	J:85083
Biological Process	GO:0097190	apoptotic signaling pathway	IDA	J:74669
Biological Process	GO:0097190	apoptotic signaling pathway	IMP	J:85083
Biological Process	GO:0097190	apoptotic signaling pathway	IDA	J:93470
Biological Process	GO:0046034	ATP metabolic process	IMP	J:133563
Biological Process	GO:0071456	cellular response to hypoxia	IBA	J:265628
Biological Process	GO:0071396	cellular response to lipid	IEP	J:133563
Biological Process	GO:0071316	cellular response to nicotine	ISO	J:164563
Biological Process	GO:0071310	cellular response to organic substance	ISO	J:83681
Biological Process	GO:0019221	cytokine-mediated signaling pathway	IDA	J:88294
Biological Process	GO:0050673	epithelial cell proliferation	IDA	J:40808
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	IGI	J:88139
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	IDA	J:78230
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	IMP	J:88294
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	IDA	J:85463
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	IMP	J:88139
Biological Process	GO:0006007	glucose catabolic process	IMP	J:85083
Biological Process	GO:0006007	glucose catabolic process	IMP	J:85083
Biological Process	GO:0042593	glucose homeostasis	IMP	J:133563
Biological Process	GO:0042593	glucose homeostasis	IMP	J:85083
Biological Process	GO:0042593	glucose homeostasis	IMP	J:85083
Biological Process	GO:0019051	induction by virus of host apoptotic process	IDA	J:93470
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	ISO	J:164563
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IMP	J:88139
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	IDA	J:93470
Biological Process	GO:0046931	pore complex assembly	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0043065	positive regulation of apoptotic process	IDA	J:194718
Biological Process	GO:0043065	positive regulation of apoptotic process	IDA	J:173139
Biological Process	GO:0043065	positive regulation of apoptotic process	ISO	J:83681
Biological Process	GO:0045579	positive regulation of B cell differentiation	IMP	J:88139
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ISO	J:164563
Biological Process	GO:0033133	positive regulation of glucokinase activity	IMP	J:133563
Biological Process	GO:1904710	positive regulation of granulosa cell apoptotic process	ISO	J:155856
Biological Process	GO:0032024	positive regulation of insulin secretion	IMP	J:133563
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	IMP	J:133563
Biological Process	GO:1902220	positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	IDA	J:194718
Biological Process	GO:0010918	positive regulation of mitochondrial membrane potential	IMP	J:133563
Biological Process	GO:1901216	positive regulation of neuron death	ISO	J:155856
Biological Process	GO:0045862	positive regulation of proteolysis	ISO	J:164563
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	ISO	J:164563
Biological Process	GO:0045582	positive regulation of T cell differentiation	IMP	J:88139
Biological Process	GO:2000078	positive regulation of type B pancreatic cell development	IMP	J:133563
Biological Process	GO:0042981	regulation of apoptotic process	IDA	J:42326
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	IMP	J:88294
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	ISO	J:164563
Biological Process	GO:0046902	regulation of mitochondrial membrane permeability	IBA	J:265628
Biological Process	GO:0001836	release of cytochrome c from mitochondria	IBA	J:265628
Biological Process	GO:0001836	release of cytochrome c from mitochondria	IMP	J:88139
Biological Process	GO:0019050	suppression by virus of host apoptotic process	IMP	J:93470
Biological Process	GO:0019050	suppression by virus of host apoptotic process	IDA	J:93470
Biological Process	GO:0044342	type B pancreatic cell proliferation	IMP	J:133563