GO Annotations Graph

• Symbol: Slc1a6
• Name: solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
• ID: MGI:1096331

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015501	glutamate:sodium symporter activity	ISO	J:164563
Molecular Function	GO:0015501	glutamate:sodium symporter activity	IBA	J:265628
Molecular Function	GO:0005314	high-affinity L-glutamate transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015183	L-aspartate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	IMP	J:87447
Molecular Function	GO:0005313	L-glutamate transmembrane transporter activity	IMP	J:87447
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0008509	monoatomic anion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015175	neutral L-amino acid transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0015293	symporter activity	IEA	J:72247
Molecular Function	GO:0015293	symporter activity	IEA	J:60000
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263454
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:263454
Cellular Component	GO:0005794	Golgi apparatus	IDA	J:158494
Cellular Component	GO:0045111	intermediate filament cytoskeleton	ISO	J:164563
Cellular Component	GO:0016020	membrane	IDA	J:158494
Cellular Component	GO:0098796	membrane protein complex	ISO	J:155856
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:263454
Cellular Component	GO:0042734	presynaptic membrane	IDA	J:263454
Biological Process	GO:0006865	amino acid transport	IEA	J:60000
Biological Process	GO:0051649	establishment of localization in cell	IMP	J:87447
Biological Process	GO:0140009	L-aspartate import across plasma membrane	ISO	J:164563
Biological Process	GO:0098712	L-glutamate import across plasma membrane	ISO	J:155856
Biological Process	GO:0098712	L-glutamate import across plasma membrane	ISO	J:164563
Biological Process	GO:0015813	L-glutamate transmembrane transport	ISO	J:155856
Biological Process	GO:0015813	L-glutamate transmembrane transport	IBA	J:265628
Biological Process	GO:0015813	L-glutamate transmembrane transport	IMP	J:87447
Biological Process	GO:0001504	neurotransmitter uptake	ISO	J:164563
Biological Process	GO:0042391	regulation of membrane potential	IMP	J:87447