GO Annotations Graph

• Symbol: Nrxn2
• Name: neurexin II
• ID: MGI:1096362

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005246	calcium channel regulator activity	IGI	J:89452
Molecular Function	GO:0005246	calcium channel regulator activity	IGI	J:89452
Molecular Function	GO:0050839	cell adhesion molecule binding	IPI	J:175310
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0097109	neuroligin family protein binding	IPI	J:175310
Molecular Function	GO:0005515	protein binding	IPI	J:249826
Molecular Function	GO:0005515	protein binding	IPI	J:171950
Molecular Function	GO:0005515	protein binding	IPI	J:171950
Molecular Function	GO:0005515	protein binding	IPI	J:171950
Molecular Function	GO:0004888	transmembrane signaling receptor activity	IDA	J:175310
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:242453
Cellular Component	GO:0098978	glutamatergic synapse	IDA	J:242453
Cellular Component	GO:0098978	glutamatergic synapse	IMP	J:242453
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0042734	presynaptic membrane	ISA	J:89452
Cellular Component	GO:0032991	protein-containing complex	IPI	J:211830
Cellular Component	GO:0032991	protein-containing complex	IPI	J:211830
Biological Process	GO:0030534	adult behavior	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IEA	J:60000
Biological Process	GO:0007268	chemical synaptic transmission	IGI	J:89452
Biological Process	GO:0007268	chemical synaptic transmission	IGI	J:89452
Biological Process	GO:0097116	gephyrin clustering involved in postsynaptic density assembly	IDA	J:175310
Biological Process	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly	IDA	J:175310
Biological Process	GO:0007269	neurotransmitter secretion	IGI	J:89452
Biological Process	GO:0007269	neurotransmitter secretion	IGI	J:89452
Biological Process	GO:0097119	postsynaptic density protein 95 clustering	IDA	J:175310
Biological Process	GO:0097104	postsynaptic membrane assembly	IDA	J:175310
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	IDA	J:242453
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	IMP	J:242453
Biological Process	GO:0098962	regulation of postsynaptic neurotransmitter receptor activity	IDA	J:242453
Biological Process	GO:0007165	signal transduction	IDA	J:175310
Biological Process	GO:0035176	social behavior	ISO	J:164563
Biological Process	GO:0007416	synapse assembly	IGI	J:89452
Biological Process	GO:0007416	synapse assembly	IGI	J:89452
Biological Process	GO:0042297	vocal learning	ISO	J:164563
Biological Process	GO:0071625	vocalization behavior	ISO	J:164563