GO Annotations Graph

• Symbol: Dll3
• Name: delta like canonical Notch ligand 3
• ID: MGI:1096877

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0005112	Notch binding	NAS	J:42455
Molecular Function	GO:0005112	Notch binding	ISO	J:155856
Molecular Function	GO:0005112	Notch binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:320690
Molecular Function	GO:0005515	protein binding	IPI	J:320690
Molecular Function	GO:0005515	protein binding	IPI	J:101173
Cellular Component	GO:0010008	endosome membrane	TAS	Reactome:R-MMU-9793875
Cellular Component	GO:0010008	endosome membrane	TAS	Reactome:R-MMU-9793917
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:320690
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0001709	cell fate determination	NAS	J:42455
Biological Process	GO:0007386	compartment pattern specification	IMP	J:77247
Biological Process	GO:0001701	in utero embryonic development	NAS	J:42455
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0048712	negative regulation of astrocyte differentiation	ISO	J:155856
Biological Process	GO:0050768	negative regulation of neurogenesis	IDA	J:42455
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	ISO	J:155856
Biological Process	GO:0007399	nervous system development	NAS	J:42455
Biological Process	GO:0007219	Notch signaling pathway	NAS	J:42455
Biological Process	GO:0007219	Notch signaling pathway	IBA	J:265628
Biological Process	GO:0048339	paraxial mesoderm development	IMP	J:107136
Biological Process	GO:0050769	positive regulation of neurogenesis	ISO	J:155856
Biological Process	GO:0001501	skeletal system development	IMP	J:75954
Biological Process	GO:0001501	skeletal system development	ISO	J:164563
Biological Process	GO:0001756	somitogenesis	IDA	J:42455
Biological Process	GO:0001756	somitogenesis	IMP	J:107136
Biological Process	GO:0009888	tissue development	IDA	J:42455