GO Annotations Graph

• Symbol: Eef1a1
• Name: eukaryotic translation elongation factor 1 alpha 1
• ID: MGI:1096881

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005516	calmodulin binding	IDA	J:250441
Molecular Function	GO:0005525	GTP binding	IEA	J:72247
Molecular Function	GO:0005525	GTP binding	IEA	J:60000
Molecular Function	GO:0003924	GTPase activity	IBA	J:265628
Molecular Function	GO:1901363	heterocyclic compound binding	ISO	J:155856
Molecular Function	GO:0042802	identical protein binding	ISO	J:155856
Molecular Function	GO:0019900	kinase binding	ISO	J:164563
Molecular Function	GO:0003729	mRNA binding	ISO	J:155856
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:192650
Molecular Function	GO:0005515	protein binding	IPI	J:143804
Molecular Function	GO:0005515	protein binding	IPI	J:233627
Molecular Function	GO:0005515	protein binding	IPI	J:145560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0005515	protein binding	IPI	J:175560
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0003746	translation elongation factor activity	IBA	J:265628
Molecular Function	GO:0000049	tRNA binding	ISO	J:164563
Cellular Component	GO:0030864	cortical actin cytoskeleton	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:192650
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:88820
Cellular Component	GO:0005829	cytosol	ISO	J:155856
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IDA	J:175560
Cellular Component	GO:0032587	ruffle membrane	ISO	J:164563
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ISO	J:164563
Biological Process	GO:0044829	positive regulation by host of viral genome replication	ISO	J:164563
Biological Process	GO:1900022	regulation of D-erythro-sphingosine kinase activity	ISO	J:164563
Biological Process	GO:0006412	translation	IBA	J:265628
Biological Process	GO:0006414	translational elongation	IBA	J:265628