GO Annotations Graph

• Symbol: Kif14
• Name: kinesin family member 14
• ID: MGI:1098226

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IDA	J:215928
Molecular Function	GO:0016887	ATP hydrolysis activity	IDA	J:215928
Molecular Function	GO:0016887	ATP hydrolysis activity	IBA	J:265628
Molecular Function	GO:0008017	microtubule binding	IDA	J:215928
Molecular Function	GO:0008017	microtubule binding	IBA	J:265628
Molecular Function	GO:0003777	microtubule motor activity	IBA	J:265628
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0030165	PDZ domain binding	ISO	J:195239
Molecular Function	GO:0008574	plus-end-directed microtubule motor activity	IDA	J:215928
Molecular Function	GO:0019901	protein kinase binding	ISO	J:164563
Molecular Function	GO:0015631	tubulin binding	IDA	J:215928
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0090543	Flemming body	ISO	J:164563
Cellular Component	GO:0005871	kinesin complex	IBA	J:265628
Cellular Component	GO:0005874	microtubule	IBA	J:265628
Cellular Component	GO:0005874	microtubule	ISO	J:195239
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0051233	spindle midzone	ISO	J:164563
Biological Process	GO:0032147	activation of protein kinase activity	ISO	J:164563
Biological Process	GO:0051301	cell division	IMP	J:215396
Biological Process	GO:0021846	cell proliferation in forebrain	IMP	J:195809
Biological Process	GO:0021695	cerebellar cortex development	IMP	J:195809
Biological Process	GO:0021685	cerebellar granular layer structural organization	IMP	J:195809
Biological Process	GO:0021693	cerebellar Purkinje cell layer structural organization	IMP	J:195809
Biological Process	GO:0021987	cerebral cortex development	IMP	J:195809
Biological Process	GO:0045184	establishment of protein localization	ISO	J:195239
Biological Process	GO:0021766	hippocampus development	IMP	J:195809
Biological Process	GO:0007018	microtubule-based movement	IBA	J:265628
Biological Process	GO:0007080	mitotic metaphase plate congression	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0033624	negative regulation of integrin activation	ISO	J:195239
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	IMP	J:195809
Biological Process	GO:0021772	olfactory bulb development	IMP	J:215396
Biological Process	GO:0021772	olfactory bulb development	IMP	J:195809
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0032467	positive regulation of cytokinesis	ISO	J:164563
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0030155	regulation of cell adhesion	ISO	J:195239
Biological Process	GO:0001558	regulation of cell growth	ISO	J:164563
Biological Process	GO:1903429	regulation of cell maturation	IMP	J:215396
Biological Process	GO:0030334	regulation of cell migration	ISO	J:195239
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0031641	regulation of myelination	IMP	J:195809
Biological Process	GO:0031641	regulation of myelination	IMP	J:215396
Biological Process	GO:0043523	regulation of neuron apoptotic process	IMP	J:215396
Biological Process	GO:0032487	regulation of Rap protein signal transduction	ISO	J:195239
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	ISO	J:164563
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	ISO	J:195239