GO Annotations Graph

• Symbol: Cenpe
• Name: centromere protein E
• ID: MGI:1098230

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0043515	kinetochore binding	IDA	J:85203
Molecular Function	GO:0043515	kinetochore binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	ISO	J:164563
Molecular Function	GO:0008017	microtubule binding	IBA	J:265628
Molecular Function	GO:0003777	microtubule motor activity	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0019901	protein kinase binding	IPI	J:85203
Cellular Component	GO:0005694	chromosome	ISO	J:164563
Cellular Component	GO:0000775	chromosome, centromeric region	ISO	J:164563
Cellular Component	GO:0000775	chromosome, centromeric region	ISO	J:86384
Cellular Component	GO:0000779	condensed chromosome, centromeric region	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0045171	intercellular bridge	ISO	J:164563
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IDA	J:85203
Cellular Component	GO:0000776	kinetochore	IDA	J:135093
Cellular Component	GO:0000776	kinetochore	IDA	J:138779
Cellular Component	GO:0005828	kinetochore microtubule	ISO	J:164563
Cellular Component	GO:0005874	microtubule	ISO	J:164563
Cellular Component	GO:0005874	microtubule	IBA	J:265628
Cellular Component	GO:0015630	microtubule cytoskeleton	ISO	J:164563
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:1990023	mitotic spindle midzone	ISO	J:164563
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0000940	outer kinetochore	IDA	J:147064
Cellular Component	GO:0051233	spindle midzone	ISO	J:164563
Biological Process	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:0008608	attachment of spindle microtubules to kinetochore	IMP	J:85203
Biological Process	GO:0008608	attachment of spindle microtubules to kinetochore	TAS	J:79594
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0007059	chromosome segregation	ISO	J:164563
Biological Process	GO:0045184	establishment of protein localization	IMP	J:85203
Biological Process	GO:0051382	kinetochore assembly	ISO	J:164563
Biological Process	GO:0099607	lateral attachment of mitotic spindle microtubules to kinetochore	ISO	J:164563
Biological Process	GO:0051310	metaphase plate congression	ISO	J:164563
Biological Process	GO:0099606	microtubule plus-end directed mitotic chromosome migration	ISO	J:164563
Biological Process	GO:0007018	microtubule-based movement	IBA	J:265628
Biological Process	GO:0000278	mitotic cell cycle	ISO	J:164563
Biological Process	GO:0000278	mitotic cell cycle	IBA	J:265628
Biological Process	GO:0007079	mitotic chromosome movement towards spindle pole	ISO	J:164563
Biological Process	GO:0007080	mitotic metaphase plate congression	ISO	J:164563
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	IMP	J:85203
Biological Process	GO:0007052	mitotic spindle organization	ISO	J:164563
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	IMP	J:81046
Biological Process	GO:0051984	positive regulation of chromosome segregation	IMP	J:85203
Biological Process	GO:0045842	positive regulation of mitotic metaphase/anaphase transition	IMP	J:85203
Biological Process	GO:0045860	positive regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0045860	positive regulation of protein kinase activity	IDA	J:85203
Biological Process	GO:0050793	regulation of developmental process	IMP	J:81046
Biological Process	GO:0030071	regulation of mitotic metaphase/anaphase transition	ISO	J:164563
Biological Process	GO:0007088	regulation of mitotic nuclear division	IMP	J:81046
Biological Process	GO:0031647	regulation of protein stability	IMP	J:196442
Biological Process	GO:0007057	spindle assembly involved in female meiosis I	IMP	J:196442