GO Annotations Graph

• Symbol: Ogdh
• Name: oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
• ID: MGI:1098267

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0031072	heat shock protein binding	ISO	J:155856
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0016491	oxidoreductase activity	IEA	J:60000
Molecular Function	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEA	J:72247
Molecular Function	GO:0034602	oxoglutarate dehydrogenase (NAD+) activity	IDA	J:121138
Molecular Function	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	ISO	J:164563
Molecular Function	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	ISO	J:155856
Molecular Function	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	IBA	J:265628
Molecular Function	GO:0051087	protein-folding chaperone binding	ISO	J:155856
Molecular Function	GO:0030976	thiamine pyrophosphate binding	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	IBA	J:265628
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IDA	J:121138
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0045252	oxoglutarate dehydrogenase complex	ISO	J:164563
Cellular Component	GO:0045252	oxoglutarate dehydrogenase complex	ISO	J:155856
Cellular Component	GO:0045252	oxoglutarate dehydrogenase complex	IBA	J:265628
Cellular Component	GO:0045252	oxoglutarate dehydrogenase complex	IMP	J:188319
Biological Process	GO:0006103	2-oxoglutarate metabolic process	ISO	J:164563
Biological Process	GO:0006103	2-oxoglutarate metabolic process	ISO	J:155856
Biological Process	GO:0021695	cerebellar cortex development	IEP	J:112617
Biological Process	GO:0006096	glycolytic process	IEA	J:60000
Biological Process	GO:0021766	hippocampus development	IEP	J:112617
Biological Process	GO:0106077	histone succinylation	ISO	J:164563
Biological Process	GO:0006734	NADH metabolic process	ISO	J:155856
Biological Process	GO:0061034	olfactory bulb mitral cell layer development	IEP	J:112617
Biological Process	GO:0021860	pyramidal neuron development	IEP	J:112617
Biological Process	GO:0021756	striatum development	IEP	J:112617
Biological Process	GO:0006104	succinyl-CoA metabolic process	ISO	J:155856
Biological Process	GO:0006104	succinyl-CoA metabolic process	ISO	J:164563
Biological Process	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	IEP	J:112617
Biological Process	GO:0021794	thalamus development	IEP	J:112617
Biological Process	GO:0006099	tricarboxylic acid cycle	ISO	J:155856
Biological Process	GO:0006099	tricarboxylic acid cycle	IBA	J:265628