GO Annotations Graph

• Symbol: Jag2
• Name: jagged 2
• ID: MGI:1098270

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0008083	growth factor activity	ISS	J:56675
Molecular Function	GO:0008083	growth factor activity	ISO	J:164563
Molecular Function	GO:0005112	Notch binding	IPI	J:88030
Molecular Function	GO:0005112	Notch binding	ISO	J:164563
Molecular Function	GO:0005112	Notch binding	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:225411
Molecular Function	GO:0005515	protein binding	IPI	J:115539
Cellular Component	GO:0016020	membrane	IDA	J:100835
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ISO	J:155856
Cellular Component	GO:0005886	plasma membrane	IDA	J:63637
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-2032379
Cellular Component	GO:0005886	plasma membrane	TAS	Reactome:R-MMU-9013059
Biological Process	GO:0009912	auditory receptor cell fate commitment	IMP	J:53432
Biological Process	GO:0007154	cell communication	IEA	J:72247
Biological Process	GO:0030154	cell differentiation	ISO	J:164563
Biological Process	GO:0001709	cell fate determination	NAS	J:63637
Biological Process	GO:1990134	epithelial cell apoptotic process involved in palatal shelf morphogenesis	IMP	J:108824
Biological Process	GO:1990134	epithelial cell apoptotic process involved in palatal shelf morphogenesis	IMP	J:108824
Biological Process	GO:0042492	gamma-delta T cell differentiation	IMP	J:56675
Biological Process	GO:0001701	in utero embryonic development	IMP	J:46930
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	IMP	J:108824
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:72247
Biological Process	GO:0007219	Notch signaling pathway	IEA	J:72247
Biological Process	GO:0007219	Notch signaling pathway	IEA	J:60000
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:98508
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	IDA	J:88030
Biological Process	GO:0030155	regulation of cell adhesion	IMP	J:108824
Biological Process	GO:0042127	regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:0042127	regulation of cell population proliferation	ISS	J:56675
Biological Process	GO:0003016	respiratory system process	IMP	J:46930
Biological Process	GO:0007605	sensory perception of sound	NAS	J:53432
Biological Process	GO:0001501	skeletal system development	IMP	J:98508
Biological Process	GO:0001501	skeletal system development	IMP	J:98508
Biological Process	GO:0007283	spermatogenesis	ISO	J:155856
Biological Process	GO:0030217	T cell differentiation	ISO	J:164563
Biological Process	GO:0045061	thymic T cell selection	ISO	J:164563
Biological Process	GO:0045061	thymic T cell selection	ISS	J:56675