GO Annotations Graph

• Symbol: Rnasel
• Name: ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
• ID: MGI:1098272

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0004519	endonuclease activity	IEA	J:60000
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0004518	nuclease activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0043021	ribonucleoprotein complex binding	IDA	J:204800
Molecular Function	GO:0003723	RNA binding	ISO	J:164563
Molecular Function	GO:0003723	RNA binding	IBA	J:265628
Molecular Function	GO:0004540	RNA nuclease activity	ISO	J:164563
Molecular Function	GO:0004540	RNA nuclease activity	ISO	J:155856
Molecular Function	GO:0004540	RNA nuclease activity	IBA	J:265628
Molecular Function	GO:0019843	rRNA binding	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005739	mitochondrion	IEA	J:60000
Cellular Component	GO:0016363	nuclear matrix	ISO	J:155856
Biological Process	GO:0051607	defense response to virus	ISO	J:164563
Biological Process	GO:0051607	defense response to virus	IBA	J:265628
Biological Process	GO:0045444	fat cell differentiation	IGI	J:204800
Biological Process	GO:0045444	fat cell differentiation	IMP	J:204800
Biological Process	GO:0006397	mRNA processing	IEA	J:72247
Biological Process	GO:0045071	negative regulation of viral genome replication	ISO	J:164563
Biological Process	GO:0045071	negative regulation of viral genome replication	IBA	J:265628
Biological Process	GO:0046326	positive regulation of glucose import	IMP	J:204800
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0043488	regulation of mRNA stability	IMP	J:204800
Biological Process	GO:0006396	RNA processing	IBA	J:265628
Biological Process	GO:0006364	rRNA processing	ISO	J:155856