GO Annotations Graph

• Symbol: Crebbp
• Name: CREB binding protein
• ID: MGI:1098280

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016407	acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0016746	acyltransferase activity	IEA	J:60000
Molecular Function	GO:0008140	cAMP response element binding protein binding	IPI	J:240310
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:98847
Molecular Function	GO:0003682	chromatin binding	IDA	J:188795
Molecular Function	GO:0031490	chromatin DNA binding	IBA	J:265628
Molecular Function	GO:0003684	damaged DNA binding	ISO	J:164563
Molecular Function	GO:0097718	disordered domain specific binding	IPI	J:230369
Molecular Function	GO:0097718	disordered domain specific binding	IPI	J:240295
Molecular Function	GO:0003677	DNA binding	IDA	J:96189
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:155856
Molecular Function	GO:0004402	histone acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0004402	histone acetyltransferase activity	ISO	J:155856
Molecular Function	GO:0004402	histone acetyltransferase activity	TAS	Reactome:R-MMU-4568768
Molecular Function	GO:0004402	histone acetyltransferase activity	TAS	Reactome:R-NUL-9626944
Molecular Function	GO:0004402	histone acetyltransferase activity	IBA	J:265628
Molecular Function	GO:0004402	histone acetyltransferase activity	IDA	J:80589
Molecular Function	GO:0004402	histone acetyltransferase activity	IDA	J:132209
Molecular Function	GO:0004402	histone acetyltransferase activity	IDA	J:75146
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0060090	molecular adaptor activity	EXP	J:326238
Molecular Function	GO:0060090	molecular adaptor activity	EXP	J:326239
Molecular Function	GO:0060090	molecular adaptor activity	EXP	J:230369
Molecular Function	GO:0043426	MRF binding	ISO	J:164563
Molecular Function	GO:0002039	p53 binding	ISO	J:164563
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	ISO	J:164563
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	TAS	Reactome:R-MMU-9617755
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	ISO	J:155856
Molecular Function	GO:0005515	protein binding	IPI	J:161286
Molecular Function	GO:0005515	protein binding	IPI	J:201464
Molecular Function	GO:0005515	protein binding	IPI	J:217891
Molecular Function	GO:0005515	protein binding	IPI	J:137458
Molecular Function	GO:0005515	protein binding	IPI	J:211655
Molecular Function	GO:0005515	protein binding	IPI	J:183225
Molecular Function	GO:0005515	protein binding	IPI	J:306714
Molecular Function	GO:0005515	protein binding	IPI	J:114021
Molecular Function	GO:0005515	protein binding	IPI	J:177210
Molecular Function	GO:0005515	protein binding	IPI	J:118800
Molecular Function	GO:0005515	protein binding	IPI	J:118816
Molecular Function	GO:0005515	protein binding	IPI	J:127192
Molecular Function	GO:0005515	protein binding	IPI	J:151998
Molecular Function	GO:0005515	protein binding	IPI	J:197481
Molecular Function	GO:0005515	protein binding	IPI	J:113916
Molecular Function	GO:0005515	protein binding	IPI	J:198705
Molecular Function	GO:0005515	protein binding	IPI	J:201736
Molecular Function	GO:0005515	protein binding	IPI	J:245250
Molecular Function	GO:0005515	protein binding	IPI	J:159136
Molecular Function	GO:0005515	protein binding	IPI	J:245388
Molecular Function	GO:0005515	protein binding	IPI	J:199993
Molecular Function	GO:0005515	protein binding	IPI	J:245363
Molecular Function	GO:0005515	protein binding	IPI	J:61379
Molecular Function	GO:0005515	protein binding	IPI	J:167070
Molecular Function	GO:0005515	protein binding	IPI	J:80589
Molecular Function	GO:0005515	protein binding	IPI	J:173620
Molecular Function	GO:0005515	protein binding	IPI	J:94611
Molecular Function	GO:0005515	protein binding	IPI	J:152281
Molecular Function	GO:0005515	protein binding	IPI	J:106776
Molecular Function	GO:0005515	protein binding	IPI	J:57302
Molecular Function	GO:0005515	protein binding	IPI	J:109095
Molecular Function	GO:0005515	protein binding	IPI	J:97384
Molecular Function	GO:0005515	protein binding	IPI	J:109095
Molecular Function	GO:0005515	protein binding	IPI	J:98014
Molecular Function	GO:0005515	protein binding	IPI	J:88316
Molecular Function	GO:0005515	protein binding	IPI	J:106848
Molecular Function	GO:0005515	protein binding	IPI	J:166840
Molecular Function	GO:0005515	protein binding	IPI	J:97384
Molecular Function	GO:0005515	protein binding	IPI	J:132209
Molecular Function	GO:0005515	protein binding	IPI	J:97384
Molecular Function	GO:0005515	protein binding	IPI	J:173620
Molecular Function	GO:0005515	protein binding	IPI	J:88272
Molecular Function	GO:0005515	protein binding	IPI	J:86566
Molecular Function	GO:0005515	protein binding	IPI	J:57302
Molecular Function	GO:0005515	protein binding	IPI	J:106848
Molecular Function	GO:0005515	protein binding	IPI	J:106848
Molecular Function	GO:0005515	protein binding	IPI	J:230369
Molecular Function	GO:0005515	protein binding	IPI	J:97384
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:71923
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:240295
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	J:173973
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:159092
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:19318
Molecular Function	GO:0046332	SMAD binding	ISO	J:155856
Molecular Function	GO:0001093	TFIIB-class transcription factor binding	IPI	J:19318
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:164563
Molecular Function	GO:0003713	transcription coactivator activity	TAS	J:113916
Molecular Function	GO:0003713	transcription coactivator activity	IBA	J:265628
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:19318
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:164563
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:155856
Molecular Function	GO:0003712	transcription coregulator activity	IEA	J:72247
Molecular Function	GO:0003714	transcription corepressor activity	ISO	J:164563
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Molecular Function	GO:0008270	zinc ion binding	IMP	J:240295
Cellular Component	GO:0000785	chromatin	IDA	J:90824
Cellular Component	GO:0000785	chromatin	IDA	J:166020
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0000123	histone acetyltransferase complex	IBA	J:265628
Cellular Component	GO:0000123	histone acetyltransferase complex	IDA	J:57302
Cellular Component	GO:0016604	nuclear body	ISO	J:164563
Cellular Component	GO:0016604	nuclear body	ISO	J:155856
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-3927825
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4395232
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-4568768
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-556760
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619441
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9617711
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9617755
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-9626944
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:94611
Cellular Component	GO:0005634	nucleus	IDA	J:80589
Cellular Component	GO:0005634	nucleus	IDA	J:74599
Cellular Component	GO:0000940	outer kinetochore	IDA	J:86777
Cellular Component	GO:0016605	PML body	ISO	J:127492
Cellular Component	GO:0032991	protein-containing complex	ISO	J:155856
Cellular Component	GO:0032991	protein-containing complex	IMP	J:230369
Cellular Component	GO:0032991	protein-containing complex	IMP	J:240295
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:19318
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	IDA	J:192962
Cellular Component	GO:0005667	transcription regulator complex	ISO	J:155856
Cellular Component	GO:0005667	transcription regulator complex	IBA	J:265628
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:80691
Cellular Component	GO:0005667	transcription regulator complex	IDA	J:109095
Biological Process	GO:0048148	behavioral response to cocaine	ISO	J:155856
Biological Process	GO:0008283	cell population proliferation	ISO	J:155856
Biological Process	GO:0035729	cellular response to hepatocyte growth factor stimulus	IDA	J:166840
Biological Process	GO:0031669	cellular response to nutrient levels	ISO	J:164563
Biological Process	GO:0034644	cellular response to UV	ISO	J:164563
Biological Process	GO:0098586	cellular response to virus	IMP	J:71923
Biological Process	GO:0060325	face morphogenesis	IMP	J:156907
Biological Process	GO:0030718	germ-line stem cell population maintenance	IMP	J:127542
Biological Process	GO:0016573	histone acetylation	IBA	J:265628
Biological Process	GO:0016570	histone modification	ISO	J:155856
Biological Process	GO:0007616	long-term memory	ISO	J:155856
Biological Process	GO:0018076	N-terminal peptidyl-lysine acetylation	ISO	J:164563
Biological Process	GO:0032688	negative regulation of interferon-beta production	IMP	J:71923
Biological Process	GO:0016479	negative regulation of transcription by RNA polymerase I	ISO	J:164563
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0048525	negative regulation of viral process	IMP	J:71923
Biological Process	GO:0038061	NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0060355	positive regulation of cell adhesion molecule production	ISO	J:155856
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	IDA	J:19318
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:155856
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	TAS	J:113916
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:113916
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:119859
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:94611
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	IDA	J:93135
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	ISO	J:155856
Biological Process	GO:0010628	positive regulation of gene expression	IGI	J:188656
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	ISO	J:155856
Biological Process	GO:1900182	positive regulation of protein localization to nucleus	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IGI	J:106776
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	ISO	J:164563
Biological Process	GO:0006473	protein acetylation	ISO	J:164563
Biological Process	GO:0031648	protein destabilization	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:71923
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:80691
Biological Process	GO:0002931	response to ischemia	ISO	J:155856
Biological Process	GO:0048511	rhythmic process	IEA	J:60000