GO Annotations Graph

• Symbol: Camk1
• Name: calcium/calmodulin-dependent protein kinase I
• ID: MGI:1098535

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005516	calmodulin binding	IBA	J:265628
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	ISO	J:155856
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	IBA	J:265628
Molecular Function	GO:0003824	catalytic activity	IEA	J:60000
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:245336
Molecular Function	GO:0005515	protein binding	IPI	J:93976
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0005622	intracellular anatomical structure	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0014069	postsynaptic density	ISO	J:155856
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0008152	metabolic process	IEA	J:60000
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0032091	negative regulation of protein binding	ISO	J:164563
Biological Process	GO:0007399	nervous system development	IEA	J:60000
Biological Process	GO:0006913	nucleocytoplasmic transport	IGI	J:136003
Biological Process	GO:0006913	nucleocytoplasmic transport	IDA	J:136003
Biological Process	GO:0006913	nucleocytoplasmic transport	IDA	J:77997
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0060999	positive regulation of dendritic spine development	ISO	J:164563
Biological Process	GO:0051149	positive regulation of muscle cell differentiation	ISO	J:164563
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:164563
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	ISO	J:164563
Biological Process	GO:1901985	positive regulation of protein acetylation	ISO	J:164563
Biological Process	GO:0046827	positive regulation of protein export from nucleus	ISO	J:164563
Biological Process	GO:0046827	positive regulation of protein export from nucleus	IDA	J:161038
Biological Process	GO:0071902	positive regulation of protein serine/threonine kinase activity	ISO	J:164563
Biological Process	GO:0051835	positive regulation of synapse structural plasticity	ISO	J:164563
Biological Process	GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IGI	J:136003
Biological Process	GO:0006468	protein phosphorylation	IDA	J:136003
Biological Process	GO:0051147	regulation of muscle cell differentiation	ISO	J:164563
Biological Process	GO:0043393	regulation of protein binding	ISO	J:164563
Biological Process	GO:0032880	regulation of protein localization	ISO	J:164563
Biological Process	GO:0050807	regulation of synapse organization	ISO	J:155856
Biological Process	GO:0007165	signal transduction	IDA	J:77997