GO Annotations Graph

• Symbol: Rif1
• Name: replication timing regulatory factor 1
• ID: MGI:1098622

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005515	protein binding	IPI	J:154829
Molecular Function	GO:0005515	protein binding	IPI	J:193247
Molecular Function	GO:0005515	protein binding	IPI	J:184123
Molecular Function	GO:0005515	protein binding	IPI	J:213416
Molecular Function	GO:0005515	protein binding	IPI	J:193246
Molecular Function	GO:0005515	protein binding	IPI	J:195061
Cellular Component	GO:0000785	chromatin	IMP	J:213416
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	IDA	J:89199
Cellular Component	GO:0140445	chromosome, telomeric repeat region	IDA	J:213416
Cellular Component	GO:0000793	condensed chromosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IEA	J:60000
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0001939	female pronucleus	IDA	J:89199
Cellular Component	GO:0001940	male pronucleus	IDA	J:89199
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:89199
Cellular Component	GO:0005634	nucleus	IDA	J:89199
Cellular Component	GO:0005634	nucleus	IDA	J:89199
Cellular Component	GO:0005634	nucleus	IDA	J:89199
Cellular Component	GO:0005634	nucleus	IDA	J:89199
Cellular Component	GO:0005634	nucleus	IDA	J:89199
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0035861	site of double-strand break	ISO	J:164563
Cellular Component	GO:0035861	site of double-strand break	IDA	J:193247
Cellular Component	GO:0035861	site of double-strand break	IDA	J:193246
Cellular Component	GO:0035861	site of double-strand break	IMP	J:195061
Cellular Component	GO:0051233	spindle midzone	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	IEP	J:163558
Biological Process	GO:0006974	DNA damage response	ISO	J:164563
Biological Process	GO:0006281	DNA repair	IEA	J:60000
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	ISO	J:164563
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	IMP	J:195061
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	IMP	J:193247
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	IDA	J:213416
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:213416
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	IMP	J:195061
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	IMP	J:193247
Biological Process	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	ISO	J:164563
Biological Process	GO:0051574	positive regulation of histone H3-K9 methylation	IMP	J:213416
Biological Process	GO:0045830	positive regulation of isotype switching	IMP	J:195061
Biological Process	GO:0045830	positive regulation of isotype switching	IMP	J:193246
Biological Process	GO:0045830	positive regulation of isotype switching	IMP	J:197099
Biological Process	GO:0035019	somatic stem cell population maintenance	IMP	J:107560
Biological Process	GO:0031509	subtelomeric heterochromatin formation	IMP	J:213416
Biological Process	GO:0000723	telomere maintenance	IMP	J:213416
Biological Process	GO:0000723	telomere maintenance	IBA	J:265628
Biological Process	GO:0043247	telomere maintenance in response to DNA damage	ISO	J:164563