GO Annotations Graph

• Symbol: Lbp
• Name: lipopolysaccharide binding protein
• ID: MGI:1098776

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0015026	coreceptor activity	ISO	J:164563
Molecular Function	GO:0008289	lipid binding	IEA	J:72247
Molecular Function	GO:0071723	lipopeptide binding	ISO	J:164563
Molecular Function	GO:0001530	lipopolysaccharide binding	ISO	J:155856
Molecular Function	GO:0001530	lipopolysaccharide binding	IBA	J:265628
Molecular Function	GO:0001530	lipopolysaccharide binding	ISO	J:73065
Molecular Function	GO:0001530	lipopolysaccharide binding	IDA	J:65470
Molecular Function	GO:0070891	lipoteichoic acid binding	ISO	J:73065
Molecular Function	GO:0005102	signaling receptor binding	IDA	J:43514
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IDA	J:139341
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IDA	J:43514
Cellular Component	GO:0005615	extracellular space	ISO	J:155856
Cellular Component	GO:0005615	extracellular space	ISO	J:164563
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0005615	extracellular space	IDA	J:123792
Cellular Component	GO:0005615	extracellular space	IDA	J:123792
Cellular Component	GO:0016020	membrane	IEA	J:60000
Biological Process	GO:0006953	acute-phase response	IMP	J:139341
Biological Process	GO:0006953	acute-phase response	IBA	J:265628
Biological Process	GO:0002752	cell surface pattern recognition receptor signaling pathway	ISO	J:164563
Biological Process	GO:0071222	cellular response to lipopolysaccharide	IMP	J:222669
Biological Process	GO:0071222	cellular response to lipopolysaccharide	ISO	J:73065
Biological Process	GO:0071223	cellular response to lipoteichoic acid	ISO	J:73065
Biological Process	GO:0042742	defense response to bacterium	IEA	J:60000
Biological Process	GO:0050829	defense response to Gram-negative bacterium	ISO	J:164563
Biological Process	GO:0050829	defense response to Gram-negative bacterium	IMP	J:43514
Biological Process	GO:0050829	defense response to Gram-negative bacterium	IBA	J:265628
Biological Process	GO:0050829	defense response to Gram-negative bacterium	IMP	J:123792
Biological Process	GO:0050830	defense response to Gram-positive bacterium	ISO	J:164563
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IMP	J:139341
Biological Process	GO:0050830	defense response to Gram-positive bacterium	IBA	J:265628
Biological Process	GO:0032490	detection of molecule of bacterial origin	ISO	J:164563
Biological Process	GO:0002376	immune system process	IEA	J:60000
Biological Process	GO:0045087	innate immune response	IMP	J:139341
Biological Process	GO:0045087	innate immune response	IBA	J:265628
Biological Process	GO:0002232	leukocyte chemotaxis involved in inflammatory response	IMP	J:123792
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0015920	lipopolysaccharide transport	ISO	J:164563
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0031663	lipopolysaccharide-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0002281	macrophage activation involved in immune response	IDA	J:139341
Biological Process	GO:0002281	macrophage activation involved in immune response	ISO	J:164563
Biological Process	GO:0002281	macrophage activation involved in immune response	IBA	J:265628
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	ISO	J:164563
Biological Process	GO:0030593	neutrophil chemotaxis	IMP	J:123792
Biological Process	GO:0032722	positive regulation of chemokine production	IMP	J:123792
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:164563
Biological Process	GO:0032757	positive regulation of interleukin-8 production	ISO	J:164563
Biological Process	GO:0043032	positive regulation of macrophage activation	ISO	J:155856
Biological Process	GO:0043032	positive regulation of macrophage activation	ISO	J:164563
Biological Process	GO:0043032	positive regulation of macrophage activation	IBA	J:265628
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	IMP	J:123792
Biological Process	GO:0060100	positive regulation of phagocytosis, engulfment	ISO	J:155856
Biological Process	GO:0060265	positive regulation of respiratory burst involved in inflammatory response	IMP	J:43514
Biological Process	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	ISO	J:164563
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IDA	J:139341
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:43514
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:222669
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:73065
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	IMP	J:123792
Biological Process	GO:0090559	regulation of membrane permeability	ISO	J:155856
Biological Process	GO:0032496	response to lipopolysaccharide	ISO	J:164563
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:43514
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:123792
Biological Process	GO:0032640	tumor necrosis factor production	IMP	J:123792