GO Annotations Graph

• Symbol: Mtm1
• Name: X-linked myotubular myopathy gene 1
• ID: MGI:1099452

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0019215	intermediate filament binding	ISO	J:164563
Molecular Function	GO:0016791	phosphatase activity	IEA	J:72247
Molecular Function	GO:0035091	phosphatidylinositol binding	ISO	J:164563
Molecular Function	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	ISO	J:164563
Molecular Function	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	IBA	J:265628
Molecular Function	GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	ISO	J:164563
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:171846
Molecular Function	GO:0005515	protein binding	IPI	J:203880
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:175210
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005768	endosome	IEA	J:60000
Cellular Component	GO:0030175	filopodium	ISO	J:164563
Cellular Component	GO:0031674	I band	IDA	J:136876
Cellular Component	GO:0005770	late endosome	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0001726	ruffle	ISO	J:164563
Biological Process	GO:0000045	autophagosome assembly	IMP	J:201107
Biological Process	GO:0016311	dephosphorylation	IEA	J:72247
Biological Process	GO:0008333	endosome to lysosome transport	ISO	J:164563
Biological Process	GO:0045109	intermediate filament organization	ISO	J:164563
Biological Process	GO:0006629	lipid metabolic process	IEA	J:60000
Biological Process	GO:0048311	mitochondrion distribution	ISO	J:164563
Biological Process	GO:0048311	mitochondrion distribution	IMP	J:171846
Biological Process	GO:0048311	mitochondrion distribution	IBA	J:265628
Biological Process	GO:0048311	mitochondrion distribution	IMP	J:136876
Biological Process	GO:0070584	mitochondrion morphogenesis	ISO	J:164563
Biological Process	GO:0070584	mitochondrion morphogenesis	IMP	J:171846
Biological Process	GO:0070584	mitochondrion morphogenesis	IBA	J:265628
Biological Process	GO:0046716	muscle cell cellular homeostasis	IMP	J:194971
Biological Process	GO:0046716	muscle cell cellular homeostasis	IBA	J:265628
Biological Process	GO:0046716	muscle cell cellular homeostasis	IMP	J:81791
Biological Process	GO:1902902	negative regulation of autophagosome assembly	IBA	J:265628
Biological Process	GO:1902902	negative regulation of autophagosome assembly	IMP	J:201107
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	IMP	J:201107
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	IMP	J:201107
Biological Process	GO:0032007	negative regulation of TOR signaling	IMP	J:201107
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	ISO	J:164563
Biological Process	GO:0048633	positive regulation of skeletal muscle tissue growth	IMP	J:201107
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	J:201107
Biological Process	GO:0006470	protein dephosphorylation	ISO	J:164563
Biological Process	GO:0043491	protein kinase B signaling	IMP	J:201107
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0044088	regulation of vacuole organization	ISO	J:164563
Biological Process	GO:0048630	skeletal muscle tissue growth	IMP	J:201107
Biological Process	GO:0031929	TOR signaling	IMP	J:201107