GO Annotations Graph

• Symbol: Ucp3
• Name: uncoupling protein 3 (mitochondrial, proton carrier)
• ID: MGI:1099787

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	IBA	J:265628
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	IMP	J:62313
Molecular Function	GO:0017077	oxidative phosphorylation uncoupler activity	IMP	J:62312
Molecular Function	GO:0005515	protein binding	IPI	J:333168
Molecular Function	GO:0015078	proton transmembrane transporter activity	IDA	J:333169
Molecular Function	GO:0015078	proton transmembrane transporter activity	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005743	mitochondrial inner membrane	IDA	J:333168
Cellular Component	GO:0031966	mitochondrial membrane	IEA	J:72247
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	HDA	J:151002
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Cellular Component	GO:0005739	mitochondrion	IMP	J:73905
Cellular Component	GO:0005739	mitochondrion	HDA	J:86816
Biological Process	GO:1990845	adaptive thermogenesis	IBA	J:265628
Biological Process	GO:0006631	fatty acid metabolic process	IMP	J:62313
Biological Process	GO:1901373	lipid hydroperoxide transport	IMP	J:163883
Biological Process	GO:1990542	mitochondrial transmembrane transport	IBA	J:265628
Biological Process	GO:0006839	mitochondrial transport	IEA	J:72247
Biological Process	GO:1902600	proton transmembrane transport	IDA	J:333169
Biological Process	GO:1902600	proton transmembrane transport	ISO	J:164563
Biological Process	GO:0009409	response to cold	IBA	J:265628
Biological Process	GO:0001666	response to hypoxia	ISO	J:155856
Biological Process	GO:0000303	response to superoxide	ISO	J:155856
Biological Process	GO:0000303	response to superoxide	IMP	J:78047