Vps4b GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Vps4b
vacuolar protein sorting 4B
MGI:1100499

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:72445
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:82243
Molecular Function	GO:0005515	protein binding	IPI	J:90848
Molecular Function	GO:0005515	protein binding	IPI	J:90848
Molecular Function	GO:0042803	protein homodimerization activity	ISO	J:164563
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:164563
Cellular Component	GO:1904949	ATPase complex	NAS	J:319973
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	IDA	J:60367
Cellular Component	GO:0005829	cytosol	IDA	J:110348
Cellular Component	GO:0005829	cytosol	IDA	J:90848
Cellular Component	GO:0005768	endosome	ISO	J:72445
Cellular Component	GO:0010008	endosome membrane	ISO	J:164563
Cellular Component	GO:0090543	Flemming body	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0030496	midbody	NAS	J:319960
Cellular Component	GO:0005643	nuclear pore	NAS	J:320797
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	NAS	J:319974
Cellular Component	GO:0000922	spindle pole	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	IMP	J:249954
Biological Process	GO:0097352	autophagosome maturation	NAS	J:320408
Biological Process	GO:0006914	autophagy	NAS	J:320141
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:249954
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0051301	cell division	IEA	J:60000
Biological Process	GO:0007417	central nervous system development	IMP	J:249954
Biological Process	GO:0030301	cholesterol transport	IMP	J:60367
Biological Process	GO:0016197	endosomal transport	IBA	J:265628
Biological Process	GO:0016197	endosomal transport	ISO	J:72445
Biological Process	GO:0007032	endosome organization	IMP	J:60367
Biological Process	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:1904903	ESCRT III complex disassembly	ISO	J:164563
Biological Process	GO:0060856	establishment of blood-brain barrier	IMP	J:249954
Biological Process	GO:0061738	late endosomal microautophagy	IMP	J:227378
Biological Process	GO:0061764	late endosome to lysosome transport via multivesicular body sorting pathway	NAS	J:320408
Biological Process	GO:0090148	membrane fission	NAS	J:319974
Biological Process	GO:0061952	midbody abscission	NAS	J:320142
Biological Process	GO:0061952	midbody abscission	ISO	J:164563
Biological Process	GO:0007080	mitotic metaphase plate congression	ISO	J:164563
Biological Process	GO:0036258	multivesicular body assembly	NAS	J:320797
Biological Process	GO:0036258	multivesicular body assembly	IMP	J:227378
Biological Process	GO:0071985	multivesicular body sorting pathway	NAS	J:320797
Biological Process	GO:0060548	negative regulation of cell death	NAS	J:320141
Biological Process	GO:0060548	negative regulation of cell death	ISO	J:164563
Biological Process	GO:1903542	negative regulation of exosomal secretion	ISO	J:164563
Biological Process	GO:0031468	nuclear membrane reassembly	NAS	J:319959
Biological Process	GO:0006997	nucleus organization	NAS	J:320142
Biological Process	GO:0006997	nucleus organization	ISO	J:164563
Biological Process	GO:0001778	plasma membrane repair	NAS	J:319966
Biological Process	GO:1903724	positive regulation of centriole elongation	ISO	J:164563
Biological Process	GO:1903543	positive regulation of exosomal secretion	ISO	J:164563
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	ISO	J:164563
Biological Process	GO:0006813	potassium ion transport	IDA	J:20181
Biological Process	GO:0051261	protein depolymerization	ISO	J:164563
Biological Process	GO:0015031	protein transport	IEA	J:60000
Biological Process	GO:0010824	regulation of centrosome duplication	ISO	J:164563
Biological Process	GO:1901673	regulation of mitotic spindle assembly	ISO	J:164563
Biological Process	GO:0033993	response to lipid	ISO	J:164563
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway	ISO	J:164563
Biological Process	GO:0007034	vacuolar transport	IMP	J:249954
Biological Process	GO:0007033	vacuole organization	IBA	J:265628
Biological Process	GO:0046761	viral budding from plasma membrane	ISO	J:164563
Biological Process	GO:0046761	viral budding from plasma membrane	IMP	J:219096
Biological Process	GO:0039702	viral budding via host ESCRT complex	ISO	J:164563

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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