GO Annotations Graph

• Symbol: Kcnj8
• Name: potassium inwardly-rectifying channel, subfamily J, member 8
• ID: MGI:1100508

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:155856
Molecular Function	GO:0015272	ATP-activated inward rectifier potassium channel activity	ISO	J:164563
Molecular Function	GO:0015272	ATP-activated inward rectifier potassium channel activity	ISO	J:155856
Molecular Function	GO:0015272	ATP-activated inward rectifier potassium channel activity	IBA	J:265628
Molecular Function	GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005242	inward rectifier potassium channel activity	IEA	J:72247
Molecular Function	GO:0017098	sulfonylurea receptor binding	ISO	J:155856
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	IEA	J:60000
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	ISO	J:164563
Molecular Function	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	ISO	J:164563
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:155856
Cellular Component	GO:0008282	inward rectifying potassium channel	ISO	J:155856
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0030016	myofibril	IDA	J:103335
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0048787	presynaptic active zone membrane	ISO	J:155856
Cellular Component	GO:0042383	sarcolemma	ISO	J:155856
Biological Process	GO:0051607	defense response to virus	IMP	J:126658
Biological Process	GO:0051607	defense response to virus	IMP	J:126658
Biological Process	GO:0051607	defense response to virus	IMP	J:126658
Biological Process	GO:0051607	defense response to virus	IMP	J:126658
Biological Process	GO:0007507	heart development	IMP	J:126658
Biological Process	GO:0098662	inorganic cation transmembrane transport	ISO	J:155856
Biological Process	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:1990573	potassium ion import across plasma membrane	ISO	J:155856
Biological Process	GO:1990573	potassium ion import across plasma membrane	ISO	J:164563
Biological Process	GO:1990573	potassium ion import across plasma membrane	IBA	J:265628
Biological Process	GO:0006813	potassium ion transport	ISO	J:155856
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	IBA	J:265628
Biological Process	GO:0043330	response to exogenous dsRNA	IMP	J:126658
Biological Process	GO:0032496	response to lipopolysaccharide	IMP	J:126658