Med1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Med1
mediator complex subunit 1
MGI:1100846

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003682	chromatin binding	ISO	J:155856
Molecular Function	GO:0003682	chromatin binding	ISO	J:164563
Molecular Function	GO:0003682	chromatin binding	IDA	J:164442
Molecular Function	GO:0003682	chromatin binding	IDA	J:164442
Molecular Function	GO:0003682	chromatin binding	IDA	J:80609
Molecular Function	GO:0031490	chromatin DNA binding	ISO	J:155856
Molecular Function	GO:0003677	DNA binding	IDA	J:96189
Molecular Function	GO:0003677	DNA binding	IDA	J:138818
Molecular Function	GO:0140297	DNA-binding transcription factor binding	ISO	J:164563
Molecular Function	GO:0140296	general transcription initiation factor binding	ISO	J:155856
Molecular Function	GO:0035035	histone acetyltransferase binding	ISO	J:155856
Molecular Function	GO:0050693	LBD domain binding	ISO	J:164563
Molecular Function	GO:0030331	nuclear estrogen receptor binding	ISO	J:164563
Molecular Function	GO:0016922	nuclear receptor binding	IPI	J:43438
Molecular Function	GO:0016922	nuclear receptor binding	ISO	J:164563
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ISO	J:164563
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	ISO	J:164563
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	IBA	J:265628
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	ISO	J:155856
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	ISO	J:164563
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	IBA	J:265628
Molecular Function	GO:0042809	nuclear vitamin D receptor binding	ISO	J:164563
Molecular Function	GO:0042809	nuclear vitamin D receptor binding	ISO	J:155856
Molecular Function	GO:0042809	nuclear vitamin D receptor binding	IBA	J:265628
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	ISO	J:164563
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	ISO	J:155856
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:262213
Molecular Function	GO:1990841	promoter-specific chromatin binding	IDA	J:181994
Molecular Function	GO:0005515	protein binding	IPI	J:178277
Molecular Function	GO:0005515	protein binding	IPI	J:222684
Molecular Function	GO:0005515	protein binding	IPI	J:43438
Molecular Function	GO:0005515	protein binding	IPI	J:201135
Molecular Function	GO:0005515	protein binding	IPI	J:137108
Molecular Function	GO:0044877	protein-containing complex binding	ISO	J:155856
Molecular Function	GO:0044877	protein-containing complex binding	IDA	J:92973
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ISO	J:155856
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	IPI	J:74328
Molecular Function	GO:0003713	transcription coactivator activity	TAS	J:62272
Molecular Function	GO:0003713	transcription coactivator activity	ISO	J:73065
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:74328
Molecular Function	GO:0003713	transcription coactivator activity	TAS	J:61840
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:92973
Molecular Function	GO:0003713	transcription coactivator activity	TAS	J:49107
Molecular Function	GO:0003713	transcription coactivator activity	IDA	J:43438
Molecular Function	GO:0001223	transcription coactivator binding	ISO	J:164563
Molecular Function	GO:0003712	transcription coregulator activity	ISO	J:164563
Molecular Function	GO:0003712	transcription coregulator activity	ISO	J:155856
Molecular Function	GO:0003712	transcription coregulator activity	IBA	J:265628
Molecular Function	GO:0003714	transcription corepressor activity	IMP	J:178277
Molecular Function	GO:0061630	ubiquitin protein ligase activity	ISO	J:155856
Cellular Component	GO:0000785	chromatin	ISO	J:155856
Cellular Component	GO:0070847	core mediator complex	ISO	J:164563
Cellular Component	GO:0016592	mediator complex	IBA	J:265628
Cellular Component	GO:0016592	mediator complex	ISO	J:88488
Cellular Component	GO:0016592	mediator complex	ISO	J:73065
Cellular Component	GO:0016592	mediator complex	IDA	J:92973
Cellular Component	GO:0016592	mediator complex	IDA	J:77765
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-556760
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:94123
Cellular Component	GO:0005634	nucleus	IDA	J:138818
Cellular Component	GO:0032993	protein-DNA complex	ISO	J:155856
Cellular Component	GO:0000151	ubiquitin ligase complex	ISO	J:155856
Biological Process	GO:0006702	androgen biosynthetic process	ISO	J:164563
Biological Process	GO:0001525	angiogenesis	IMP	J:74328
Biological Process	GO:0009887	animal organ morphogenesis	IMP	J:62272
Biological Process	GO:0031100	animal organ regeneration	IMP	J:123863
Biological Process	GO:0007420	brain development	IMP	J:61840
Biological Process	GO:0043010	camera-type eye development	IMP	J:86857
Biological Process	GO:0000902	cell morphogenesis	ISO	J:164563
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ISO	J:164563
Biological Process	GO:0035729	cellular response to hepatocyte growth factor stimulus	IMP	J:123863
Biological Process	GO:0071383	cellular response to steroid hormone stimulus	ISO	J:164563
Biological Process	GO:0097067	cellular response to thyroid hormone stimulus	ISO	J:155856
Biological Process	GO:0097067	cellular response to thyroid hormone stimulus	ISO	J:164563
Biological Process	GO:0097067	cellular response to thyroid hormone stimulus	IBA	J:265628
Biological Process	GO:0035050	embryonic heart tube development	IMP	J:86857
Biological Process	GO:0035162	embryonic hemopoiesis	IMP	J:86857
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	IMP	J:86857
Biological Process	GO:0001892	embryonic placenta development	IMP	J:86857
Biological Process	GO:0048822	enucleate erythrocyte development	IMP	J:167145
Biological Process	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	IMP	J:98047
Biological Process	GO:0048821	erythrocyte development	IMP	J:74328
Biological Process	GO:0048821	erythrocyte development	IMP	J:118300
Biological Process	GO:0045444	fat cell differentiation	ISO	J:73065
Biological Process	GO:0045444	fat cell differentiation	IMP	J:76817
Biological Process	GO:0045023	G0 to G1 transition	IMP	J:123863
Biological Process	GO:0007507	heart development	IMP	J:61840
Biological Process	GO:0060218	hematopoietic stem cell differentiation	IMP	J:111900
Biological Process	GO:0001701	in utero embryonic development	IMP	J:86857
Biological Process	GO:0030518	intracellular steroid hormone receptor signaling pathway	ISO	J:164563
Biological Process	GO:0030216	keratinocyte differentiation	ISO	J:164563
Biological Process	GO:0007595	lactation	IMP	J:98047
Biological Process	GO:0002088	lens development in camera-type eye	IMP	J:74328
Biological Process	GO:0001889	liver development	IMP	J:86857
Biological Process	GO:0060745	mammary gland branching involved in pregnancy	IMP	J:98047
Biological Process	GO:0060744	mammary gland branching involved in thelarche	IMP	J:98047
Biological Process	GO:0033598	mammary gland epithelial cell proliferation	IMP	J:98407
Biological Process	GO:0033598	mammary gland epithelial cell proliferation	IMP	J:159303
Biological Process	GO:0035855	megakaryocyte development	IMP	J:74328
Biological Process	GO:0030224	monocyte differentiation	IMP	J:111900
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	IMP	J:178277
Biological Process	GO:0007275	multicellular organism development	IMP	J:61840
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:178277
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	ISO	J:164563
Biological Process	GO:0045665	negative regulation of neuron differentiation	IMP	J:178277
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	IMP	J:178277
Biological Process	GO:0035357	peroxisome proliferator activated receptor signaling pathway	IMP	J:94123
Biological Process	GO:0008284	positive regulation of cell population proliferation	IMP	J:61840
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	ISO	J:164563
Biological Process	GO:0070318	positive regulation of G0 to G1 transition	IMP	J:123863
Biological Process	GO:0010628	positive regulation of gene expression	ISO	J:164563
Biological Process	GO:2000347	positive regulation of hepatocyte proliferation	IMP	J:123863
Biological Process	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	IMP	J:159303
Biological Process	GO:0045618	positive regulation of keratinocyte differentiation	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:155856
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:73065
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:92973
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IMP	J:172179
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	IDA	J:74328
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	NAS	J:320035
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	NAS	J:320035
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	ISO	J:164563
Biological Process	GO:0060335	positive regulation of type II interferon-mediated signaling pathway	IMP	J:137108
Biological Process	GO:0006606	protein import into nucleus	IMP	J:128919
Biological Process	GO:0006606	protein import into nucleus	IMP	J:111289
Biological Process	GO:0016567	protein ubiquitination	ISO	J:155856
Biological Process	GO:0006355	regulation of DNA-templated transcription	TAS	J:62272
Biological Process	GO:0006355	regulation of DNA-templated transcription	IDA	J:43438
Biological Process	GO:0006355	regulation of DNA-templated transcription	IMP	J:61840
Biological Process	GO:0006355	regulation of DNA-templated transcription	TAS	J:49107
Biological Process	GO:2001141	regulation of RNA biosynthetic process	ISO	J:164563
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	IBA	J:265628
Biological Process	GO:0070562	regulation of vitamin D receptor signaling pathway	IMP	J:111900
Biological Process	GO:0003406	retinal pigment epithelium development	IMP	J:74328
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	NAS	J:320035
Biological Process	GO:0006590	thyroid hormone generation	IMP	J:61840
Biological Process	GO:0002154	thyroid hormone mediated signaling pathway	ISO	J:164563
Biological Process	GO:0006366	transcription by RNA polymerase II	TAS	J:262213
Biological Process	GO:0006366	transcription by RNA polymerase II	IC	J:77765
Biological Process	GO:0003222	ventricular trabecula myocardium morphogenesis	IMP	J:74328

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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