GO Annotations Graph

• Symbol: Slc18a3
• Name: solute carrier family 18 (vesicular monoamine), member 3
• ID: MGI:1101061

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005277	acetylcholine transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0005277	acetylcholine transmembrane transporter activity	IBA	J:265628
Molecular Function	GO:0005278	acetylcholine:proton antiporter activity	ISO	J:155856
Molecular Function	GO:0005278	acetylcholine:proton antiporter activity	ISO	J:164563
Molecular Function	GO:0008504	monoamine transmembrane transporter activity	TAS	J:44549
Molecular Function	GO:0015311	monoamine:proton antiporter activity	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:233936
Cellular Component	GO:0030121	AP-1 adaptor complex	ISO	J:155856
Cellular Component	GO:0030121	AP-1 adaptor complex	IBA	J:265628
Cellular Component	GO:0030122	AP-2 adaptor complex	ISO	J:155856
Cellular Component	GO:0030122	AP-2 adaptor complex	IBA	J:265628
Cellular Component	GO:0030424	axon	ISO	J:155856
Cellular Component	GO:0043679	axon terminus	ISO	J:155856
Cellular Component	GO:0098981	cholinergic synapse	ISO	J:155856
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:263491
Cellular Component	GO:0098981	cholinergic synapse	EXP	J:263491
Cellular Component	GO:0098981	cholinergic synapse	IDA	J:263491
Cellular Component	GO:0005737	cytoplasm	IDA	J:173338
Cellular Component	GO:0031410	cytoplasmic vesicle	ISO	J:155856
Cellular Component	GO:0031594	neuromuscular junction	ISO	J:155856
Cellular Component	GO:0043005	neuron projection	IDA	J:101575
Cellular Component	GO:0043005	neuron projection	IDA	J:101575
Cellular Component	GO:0008021	synaptic vesicle	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0030672	synaptic vesicle membrane	ISO	J:155856
Cellular Component	GO:0043195	terminal bouton	IBA	J:265628
Cellular Component	GO:0043195	terminal bouton	IDA	J:50608
Biological Process	GO:0015870	acetylcholine transport	ISO	J:155856
Biological Process	GO:0051630	acetylcholine uptake	ISO	J:155856
Biological Process	GO:0051630	acetylcholine uptake	ISO	J:164563
Biological Process	GO:0007268	chemical synaptic transmission	IBA	J:265628
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	ISO	J:155856
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	IDA	J:263491
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	EXP	J:263491
Biological Process	GO:0098700	neurotransmitter loading into synaptic vesicle	IDA	J:263491
Biological Process	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission	IMP	J:153908
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	IMP	J:190370
Biological Process	GO:1904398	positive regulation of neuromuscular junction development	IMP	J:153908
Biological Process	GO:0051610	serotonin uptake	ISO	J:164563