GO Annotations Graph

• Symbol: Ltbp3
• Name: latent transforming growth factor beta binding protein 3
• ID: MGI:1101355

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005509	calcium ion binding	IEA	J:72247
Molecular Function	GO:0019838	growth factor binding	IEA	J:60000
Molecular Function	GO:0050431	transforming growth factor beta binding	ISO	J:164563
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ISO	J:164563
Cellular Component	GO:0031012	extracellular matrix	ISA	J:24946
Cellular Component	GO:0005576	extracellular region	IDA	J:24946
Biological Process	GO:0030282	bone mineralization	IMP	J:76213
Biological Process	GO:0060349	bone morphogenesis	IMP	J:76213
Biological Process	GO:0060349	bone morphogenesis	IMP	J:163721
Biological Process	GO:0046849	bone remodeling	IMP	J:76213
Biological Process	GO:0002062	chondrocyte differentiation	IMP	J:76213
Biological Process	GO:0060430	lung saccule development	IMP	J:99949
Biological Process	GO:0030502	negative regulation of bone mineralization	IMP	J:76213
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	IMP	J:76213
Biological Process	GO:0045780	positive regulation of bone resorption	IMP	J:123830
Biological Process	GO:2000741	positive regulation of mesenchymal stem cell differentiation	ISO	J:164563
Biological Process	GO:1902462	positive regulation of mesenchymal stem cell proliferation	ISO	J:164563
Biological Process	GO:0001501	skeletal system development	IMP	J:79920
Biological Process	GO:0036363	transforming growth factor beta activation	ISO	J:164563
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IPI	J:24946
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	IMP	J:79920