GO Annotations Graph

• Symbol: Diaph1
• Name: diaphanous related formin 1
• ID: MGI:1194490

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0003779	actin binding	IDA	J:88572
Molecular Function	GO:0042802	identical protein binding	IPI	J:190007
Molecular Function	GO:0042802	identical protein binding	IPI	J:84868
Molecular Function	GO:0042802	identical protein binding	IPI	J:247435
Molecular Function	GO:0005522	profilin binding	IDA	J:41124
Molecular Function	GO:0005515	protein binding	IPI	J:139152
Molecular Function	GO:0005515	protein binding	IPI	J:62164
Molecular Function	GO:0005515	protein binding	IPI	J:196104
Molecular Function	GO:0005515	protein binding	IPI	J:150313
Molecular Function	GO:0005515	protein binding	IPI	J:197312
Molecular Function	GO:0005515	protein binding	IPI	J:41124
Molecular Function	GO:0031267	small GTPase binding	IDA	J:41124
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0044325	transmembrane transporter binding	IPI	J:182402
Cellular Component	GO:0005884	actin filament	IBA	J:265628
Cellular Component	GO:0005903	brush border	IDA	J:219622
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IDA	J:265603
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0072686	mitotic spindle	ISO	J:164563
Cellular Component	GO:0043005	neuron projection	IDA	J:139152
Cellular Component	GO:0005634	nucleus	IDA	J:265603
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0098793	presynapse	IMP	J:256141
Cellular Component	GO:0032587	ruffle membrane	IDA	J:41124
Cellular Component	GO:0045202	synapse	IMP	J:256141
Biological Process	GO:0030036	actin cytoskeleton organization	IDA	J:265603
Biological Process	GO:0030036	actin cytoskeleton organization	IDA	J:41124
Biological Process	GO:0007015	actin filament organization	IEA	J:72247
Biological Process	GO:0030041	actin filament polymerization	IDA	J:265603
Biological Process	GO:0030041	actin filament polymerization	IBA	J:265628
Biological Process	GO:0030041	actin filament polymerization	IDA	J:88572
Biological Process	GO:0007420	brain development	IMP	J:228552
Biological Process	GO:0016043	cellular component organization	IEA	J:72247
Biological Process	GO:0071420	cellular response to histamine	ISO	J:164563
Biological Process	GO:0007010	cytoskeleton organization	ISO	J:164563
Biological Process	GO:0007010	cytoskeleton organization	IDA	J:265603
Biological Process	GO:0031175	neuron projection development	IDA	J:139152
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:155856
Biological Process	GO:0035372	protein localization to microtubule	ISO	J:164563
Biological Process	GO:0008360	regulation of cell shape	ISO	J:164563
Biological Process	GO:0051493	regulation of cytoskeleton organization	ISO	J:164563
Biological Process	GO:0032886	regulation of microtubule-based process	ISO	J:164563
Biological Process	GO:0051279	regulation of release of sequestered calcium ion into cytosol	ISO	J:164563
Biological Process	GO:0007605	sensory perception of sound	IEA	J:60000
Biological Process	GO:0048488	synaptic vesicle endocytosis	IMP	J:256141
Biological Process	GO:0048488	synaptic vesicle endocytosis	IDA	J:256141
Biological Process	GO:0048488	synaptic vesicle endocytosis	IDA	J:256141