GO Annotations Graph

• Symbol: Haspin
• Name: histone H3 associated protein kinase
• ID: MGI:1194498

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IDA	J:55557
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0003677	DNA binding	IDA	J:55557
Molecular Function	GO:0072354	histone H3T3 kinase activity	ISO	J:164563
Molecular Function	GO:0072354	histone H3T3 kinase activity	IBA	J:265628
Molecular Function	GO:0035173	histone kinase activity	IMP	J:220372
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004672	protein kinase activity	ISO	J:164563
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IDA	J:55557
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005856	cytoskeleton	IEA	J:60000
Cellular Component	GO:0001673	male germ cell nucleus	IDA	J:55557
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IDA	J:55557
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005819	spindle	ISO	J:164563
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0070192	chromosome organization involved in meiotic cell cycle	IMP	J:220372
Biological Process	GO:0010467	gene expression	IMP	J:220372
Biological Process	GO:0045143	homologous chromosome segregation	IMP	J:220372
Biological Process	GO:0035556	intracellular signal transduction	IDA	J:55557
Biological Process	GO:0035556	intracellular signal transduction	ISO	J:164563
Biological Process	GO:0035556	intracellular signal transduction	IBA	J:265628
Biological Process	GO:1903046	meiotic cell cycle process	IMP	J:220372
Biological Process	GO:0007132	meiotic metaphase I	IMP	J:220372
Biological Process	GO:0000278	mitotic cell cycle	IBA	J:265628
Biological Process	GO:0007064	mitotic sister chromatid cohesion	ISO	J:164563
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	ISO	J:164563
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	IDA	J:55557
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0071459	protein localization to chromosome, centromeric region	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	ISO	J:164563
Biological Process	GO:0006468	protein phosphorylation	IDA	J:55557
Biological Process	GO:0006468	protein phosphorylation	IMP	J:220372