GO Annotations Graph

• Symbol: Atp2a3
• Name: ATPase, Ca++ transporting, ubiquitous
• ID: MGI:1194503

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0016887	ATP hydrolysis activity	IEA	J:72247
Molecular Function	GO:0015085	calcium ion transmembrane transporter activity	ISO	J:155856
Molecular Function	GO:0015085	calcium ion transmembrane transporter activity	ISO	J:164563
Molecular Function	GO:0030899	calcium-dependent ATPase activity	ISO	J:155856
Molecular Function	GO:0030899	calcium-dependent ATPase activity	ISO	J:164563
Molecular Function	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	ISO	J:164563
Molecular Function	GO:0046872	metal ion binding	IEA	J:60000
Molecular Function	GO:0000166	nucleotide binding	IEA	J:72247
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005388	P-type calcium transporter activity	ISO	J:164563
Molecular Function	GO:0005388	P-type calcium transporter activity	ISO	J:155856
Molecular Function	GO:0005388	P-type calcium transporter activity	IBA	J:265628
Molecular Function	GO:0005515	protein binding	IPI	J:217579
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:164563
Molecular Function	GO:0005215	transporter activity	IEA	J:72247
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:79287
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0031090	organelle membrane	ISO	J:164563
Cellular Component	GO:0016529	sarcoplasmic reticulum	ISO	J:164563
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	ISO	J:164563
Biological Process	GO:0070588	calcium ion transmembrane transport	ISO	J:164563
Biological Process	GO:0070588	calcium ion transmembrane transport	ISO	J:155856
Biological Process	GO:0070588	calcium ion transmembrane transport	IBA	J:265628
Biological Process	GO:0006816	calcium ion transport	IEA	J:72247
Biological Process	GO:0006816	calcium ion transport	IEA	J:60000
Biological Process	GO:1903515	calcium ion transport from cytosol to endoplasmic reticulum	ISO	J:164563
Biological Process	GO:0032469	endoplasmic reticulum calcium ion homeostasis	ISO	J:155856
Biological Process	GO:0006874	intracellular calcium ion homeostasis	ISO	J:164563
Biological Process	GO:0006874	intracellular calcium ion homeostasis	IBA	J:265628
Biological Process	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	ISO	J:164563
Biological Process	GO:0006811	monoatomic ion transport	IEA	J:60000
Biological Process	GO:1900121	negative regulation of receptor binding	ISO	J:164563