GO Annotations Graph

• Symbol: Psmb5
• Name: proteasome (prosome, macropain) subunit, beta type 5
• ID: MGI:1194513

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0004175	endopeptidase activity	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0008233	peptidase activity	IDA	J:91425
Molecular Function	GO:0008233	peptidase activity	ISO	J:121869
Molecular Function	GO:0004298	threonine-type endopeptidase activity	IEA	J:60000
Molecular Function	GO:0004298	threonine-type endopeptidase activity	IEA	J:72247
Cellular Component	GO:0005813	centrosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9008115
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-MMU-9009438
Cellular Component	GO:0005829	cytosol	TAS	Reactome:R-NUL-1236945
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-9008717
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0000502	proteasome complex	ISO	J:164563
Cellular Component	GO:0005839	proteasome core complex	IDA	J:188902
Cellular Component	GO:0005839	proteasome core complex	ISO	J:164563
Cellular Component	GO:0005839	proteasome core complex	IDA	J:91425
Cellular Component	GO:0005839	proteasome core complex	IDA	J:162790
Cellular Component	GO:0005839	proteasome core complex	IDA	J:121869
Cellular Component	GO:0019774	proteasome core complex, beta-subunit complex	IBA	J:265628
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	J:91425
Biological Process	GO:0006508	proteolysis	ISO	J:121869
Biological Process	GO:0051603	proteolysis involved in protein catabolic process	IEA	J:72247
Biological Process	GO:0006979	response to oxidative stress	IDA	J:91425