GO Annotations Graph

• Symbol: Rbbp4
• Name: retinoblastoma binding protein 4, chromatin remodeling factor
• ID: MGI:1194912

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	ISO	J:164563
Molecular Function	GO:0042393	histone binding	ISO	J:164563
Molecular Function	GO:0042393	histone binding	IBA	J:265628
Molecular Function	GO:0042826	histone deacetylase binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:237908
Molecular Function	GO:0005515	protein binding	IPI	J:319940
Molecular Function	GO:0005515	protein binding	IPI	J:227373
Molecular Function	GO:0005515	protein binding	IPI	J:87046
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	J:237908
Cellular Component	GO:1904949	ATPase complex	ISO	J:164563
Cellular Component	GO:0033186	CAF-1 complex	ISO	J:164563
Cellular Component	GO:0000785	chromatin	ISO	J:164563
Cellular Component	GO:0005694	chromosome	IEA	J:60000
Cellular Component	GO:0000781	chromosome, telomeric region	ISO	J:164563
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:157724
Cellular Component	GO:0035098	ESC/E(Z) complex	ISO	J:164563
Cellular Component	GO:0035098	ESC/E(Z) complex	IBA	J:265628
Cellular Component	GO:0035098	ESC/E(Z) complex	IDA	J:281161
Cellular Component	GO:0000118	histone deacetylase complex	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	ISO	J:164563
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617960
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5617990
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619411
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619424
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619434
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619436
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619437
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619438
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-5619441
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-573336
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-573376
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-573383
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810138
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810150
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810169
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-MMU-6810170
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-573373
Cellular Component	GO:0005654	nucleoplasm	TAS	Reactome:R-NUL-573385
Cellular Component	GO:0005634	nucleus	IDA	J:237908
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	NAS	J:243422
Cellular Component	GO:0005634	nucleus	NAS	J:114774
Cellular Component	GO:0005634	nucleus	ISO	J:155856
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005634	nucleus	IDA	J:168362
Cellular Component	GO:0005634	nucleus	IDA	J:227373
Cellular Component	GO:0016581	NuRD complex	NAS	J:319987
Cellular Component	GO:0016581	NuRD complex	ISO	J:164563
Cellular Component	GO:0016581	NuRD complex	IBA	J:265628
Cellular Component	GO:0016581	NuRD complex	IDA	J:87046
Cellular Component	GO:0016589	NURF complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0016580	Sin3 complex	NAS	J:243422
Biological Process	GO:0007420	brain development	NAS	J:114774
Biological Process	GO:0007049	cell cycle	IEA	J:60000
Biological Process	GO:0006325	chromatin organization	IEA	J:60000
Biological Process	GO:0006338	chromatin remodeling	ISO	J:164563
Biological Process	GO:0006338	chromatin remodeling	IBA	J:265628
Biological Process	GO:0006338	chromatin remodeling	TAS	J:87046
Biological Process	GO:0006260	DNA replication	IEA	J:60000
Biological Process	GO:0006335	DNA replication-dependent chromatin assembly	ISO	J:164563
Biological Process	GO:0016575	histone deacetylation	ISO	J:164563
Biological Process	GO:0016575	histone deacetylation	IBA	J:265628
Biological Process	GO:0030336	negative regulation of cell migration	NAS	J:320045
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NAS	J:319679
Biological Process	GO:1902455	negative regulation of stem cell population maintenance	NAS	J:243422
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NAS	J:320043
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NAS	J:320044
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	NAS	J:320045
Biological Process	GO:0006334	nucleosome assembly	ISO	J:164563
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NAS	J:156393
Biological Process	GO:1902459	positive regulation of stem cell population maintenance	NAS	J:243422
Biological Process	GO:0042659	regulation of cell fate specification	NAS	J:319679
Biological Process	GO:0006355	regulation of DNA-templated transcription	ISO	J:164563
Biological Process	GO:0006355	regulation of DNA-templated transcription	IBA	J:265628
Biological Process	GO:2000736	regulation of stem cell differentiation	NAS	J:319679