GO Annotations Graph

• Symbol: Ttk
• Name: Ttk protein kinase
• ID: MGI:1194921

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	IEA	J:72247
Molecular Function	GO:0005524	ATP binding	IEA	J:60000
Molecular Function	GO:0042802	identical protein binding	IPI	J:173618
Molecular Function	GO:0016301	kinase activity	IEA	J:60000
Molecular Function	GO:0043515	kinetochore binding	IMP	J:216365
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0004672	protein kinase activity	IEA	J:72247
Molecular Function	GO:0004674	protein serine/threonine kinase activity	IBA	J:265628
Molecular Function	GO:0004712	protein serine/threonine/tyrosine kinase activity	IBA	J:265628
Molecular Function	GO:0004712	protein serine/threonine/tyrosine kinase activity	IDA	J:43402
Molecular Function	GO:0004713	protein tyrosine kinase activity	IEA	J:60000
Molecular Function	GO:0016740	transferase activity	IEA	J:60000
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0000776	kinetochore	IBA	J:265628
Cellular Component	GO:0000776	kinetochore	IDA	J:173618
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Biological Process	GO:0007059	chromosome segregation	IBA	J:265628
Biological Process	GO:0051304	chromosome separation	IEA	J:72247
Biological Process	GO:0016321	female meiosis chromosome segregation	IMP	J:173618
Biological Process	GO:0098768	meiotic prometaphase I	IMP	J:173618
Biological Process	GO:0033316	meiotic spindle assembly checkpoint signaling	IBA	J:265628
Biological Process	GO:0033316	meiotic spindle assembly checkpoint signaling	IMP	J:173618
Biological Process	GO:0007093	mitotic cell cycle checkpoint signaling	IEA	J:72247
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	IBA	J:265628
Biological Process	GO:0007094	mitotic spindle assembly checkpoint signaling	IMP	J:216365
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IBA	J:265628
Biological Process	GO:0018105	peptidyl-serine phosphorylation	IDA	J:43402
Biological Process	GO:0018107	peptidyl-threonine phosphorylation	IDA	J:43402
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	IDA	J:43402
Biological Process	GO:0016310	phosphorylation	IEA	J:60000
Biological Process	GO:0046777	protein autophosphorylation	IDA	J:43402
Biological Process	GO:0034502	protein localization to chromosome	IMP	J:173618
Biological Process	GO:0034501	protein localization to kinetochore	IBA	J:265628
Biological Process	GO:0034501	protein localization to kinetochore	IMP	J:173618
Biological Process	GO:1903096	protein localization to meiotic spindle midzone	IMP	J:173618
Biological Process	GO:0006468	protein phosphorylation	IEA	J:72247
Biological Process	GO:0071173	spindle assembly checkpoint signaling	IMP	J:326154