GO Annotations Graph

• Symbol: Sigmar1
• Name: sigma non-opioid intracellular receptor 1
• ID: MGI:1195268

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

---

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

---

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0042802	identical protein binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:197477
Molecular Function	GO:0005515	protein binding	IPI	J:261054
Molecular Function	GO:0005515	protein binding	IPI	J:182494
Molecular Function	GO:0038023	signaling receptor activity	IDA	J:89669
Cellular Component	GO:0030054	cell junction	IEA	J:60000
Cellular Component	GO:0042995	cell projection	IEA	J:60000
Cellular Component	GO:0031410	cytoplasmic vesicle	IEA	J:60000
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IBA	J:265628
Cellular Component	GO:0005811	lipid droplet	IEA	J:60000
Cellular Component	GO:0016020	membrane	ISO	J:164563
Cellular Component	GO:0005635	nuclear envelope	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IEA	J:60000
Cellular Component	GO:0014069	postsynaptic density	IDA	J:159702
Cellular Component	GO:0014069	postsynaptic density	ISO	J:164563
Cellular Component	GO:0045211	postsynaptic membrane	IEA	J:60000
Cellular Component	GO:0045202	synapse	IEA	J:60000
Biological Process	GO:0036474	cell death in response to hydrogen peroxide	IMP	J:261054
Biological Process	GO:0006869	lipid transport	IEA	J:60000
Biological Process	GO:0007399	nervous system development	ISO	J:155856
Biological Process	GO:0070207	protein homotrimerization	ISO	J:164563
Biological Process	GO:0043523	regulation of neuron apoptotic process	ISO	J:164563