GO Annotations Graph

• Symbol: Eda
• Name: ectodysplasin-A
• ID: MGI:1195272

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0038177	death receptor agonist activity	ISO	J:164563
Molecular Function	GO:0038177	death receptor agonist activity	IBA	J:265628
Molecular Function	GO:0005123	death receptor binding	ISO	J:164563
Molecular Function	GO:0005123	death receptor binding	IBA	J:265628
Molecular Function	GO:0005102	signaling receptor binding	ISO	J:164563
Molecular Function	GO:0005164	tumor necrosis factor receptor binding	IEA	J:72247
Cellular Component	GO:0045177	apical part of cell	IDA	J:105968
Cellular Component	GO:0005581	collagen trimer	IEA	J:60000
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IDA	J:58581
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005615	extracellular space	IBA	J:265628
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0005811	lipid droplet	ISO	J:164563
Cellular Component	GO:0016020	membrane	IEA	J:72247
Cellular Component	GO:0016020	membrane	IEA	J:60000
Cellular Component	GO:0005886	plasma membrane	IDA	J:58581
Biological Process	GO:0048513	animal organ development	IBA	J:265628
Biological Process	GO:0060070	canonical Wnt signaling pathway	IMP	J:151982
Biological Process	GO:0030154	cell differentiation	IEA	J:60000
Biological Process	GO:0007160	cell-matrix adhesion	IDA	J:58581
Biological Process	GO:0019221	cytokine-mediated signaling pathway	ISO	J:164563
Biological Process	GO:0010467	gene expression	IMP	J:129949
Biological Process	GO:0001942	hair follicle development	IMP	J:140329
Biological Process	GO:0001942	hair follicle development	IGI	J:140329
Biological Process	GO:0001942	hair follicle development	IMP	J:6308
Biological Process	GO:0060789	hair follicle placode formation	IGI	J:151982
Biological Process	GO:0006955	immune response	IEA	J:72247
Biological Process	GO:0007275	multicellular organism development	IEA	J:60000
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	ISO	J:164563
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:104871
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	IMP	J:12999
Biological Process	GO:0043473	pigmentation	IMP	MGI:MGI:65389
Biological Process	GO:0043473	pigmentation	IMP	J:5295
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	IMP	J:151982
Biological Process	GO:0010628	positive regulation of gene expression	IDA	J:138365
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IMP	J:140329
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ISO	J:164563
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	IDA	J:105968
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	ISO	J:164563
Biological Process	GO:0060662	salivary gland cavitation	IDA	J:105968
Biological Process	GO:0043588	skin development	IMP	J:129949
Biological Process	GO:0061153	trachea gland development	IMP	J:119848